Immunosensing by colorimetric darkfield microscopy of individual gold nanoparticle-conjugates

被引：11

作者：

Ungureanu, Felicia ^{[1
]}

Wasserberg, Dorothee ^{[1
]}

Yang, Ni ^{[2
,3
]}

Verdoold, Remco ^{[1
]}

Kooyman, Rob P. H. ^{[1
]}

机构：

[1] Univ Twente, NanoBioPhys Grp, MESA Inst, NL-7522 ND Enschede, Netherlands

[2] Univ Alberta, Dept Chem, Chem Ctr W4 09, Edmonton, AB T6G 2G2, Canada

[3] Natl Inst Nanotechnol Devices & Sensors, Genom Hlth Initiat, Edmonton Res Facil, Edmonton, AB T6G 2M9, Canada

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2010年 / 150卷 / 02期

关键词：

Gold nanoparticles; Colorimetric darkfield microscopy; Immunosensor; Parallel detection; Affinity constant; SURFACE-PLASMON RESONANCE; OPTICAL-PROPERTIES; SILVER NANOPARTICLES; SPECTROSCOPY; DEPENDENCE; BINDING; ABSORPTION; SERUM; SIZE;

D O I：

10.1016/j.snb.2010.08.044

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A new (generic) sensor platform introduced using gold colorimetric data showed that binding events of individual particles could be discerned for about 40% of the available binding sites while reference data showed less than 005% binding Endpoint SEM images of the sample and reference binding couples corroborate our findings (C) 2010 Elsevier B V All rights reserved

引用

页码：529 / 536

页数：8

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