Patient specific drug sensitivity to novel treatment approaches in ovarian cancer ex vivo 3D tumor cultures

被引：0
|
作者：
Grillet, Fanny [1 ]
Jariani, Abbas [2 ]
Overkamp, Juul [1 ]
Daszkiewicz, Lidia [1 ]
Yan, Kuan [1 ]
Price, Leo [1 ]
Vader, Willemijn [2 ]
机构：
[1] OcellO BV, Leiden, Netherlands
[2] VitroScan BV, Leiden, Netherlands
来源：
MOLECULAR CANCER THERAPEUTICS | 2019年 / 18卷 / 12期
关键词：
D O I：
10.1158/1535-7163.TARG-19-B139
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
B139
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Advanced Ovarian Cancer Displays Functional Intratumor Heterogeneity That Correlates to Ex Vivo Drug Sensitivity
    O'Donnell, Rachel L.
    Kaufmann, Angelika
    Woodhouse, Laura
    McCormick, Aiste
    Cross, Paul A.
    Edmondson, Richard J.
    Curtin, Nicola J.
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2016, 26 (06) : 1004 - 1011
  • [32] Expanding the 3D ex vivo patient tissue platform toolbox for (immuno)-oncology drug testing
    Beztsinna, Nataliia
    Basten, Sander
    Aksoy, Ezgi Kaya
    Meesters, Niels
    Timiliotis, Stefanos
    van der Meer, Donny
    Yan, Kuan
    Spanjaard, Emma
    Vader, Willemijn
    Price, Leo S.
    [J]. CANCER RESEARCH, 2023, 83 (07)
  • [33] Ex vivo assessment of cancer drug sensitivity in epithelial ovarian cancer and its association with histopathological type, treatment history and clinical outcome
    Bjersand, Kathrine
    Blom, Kristin
    Poromaa, Inger Sundstroem
    Stalberg, Karin
    Lejon, Ann-Marie
    Baeckman, Fatma
    Nyberg, Asa
    Andersson, Claes
    Larsson, Rolf
    Nygren, Peter
    [J]. INTERNATIONAL JOURNAL OF ONCOLOGY, 2022, 61 (04)
  • [34] Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM
    Peterziel, Heike
    Jamaladdin, Nora
    ElHarouni, Dina
    Gerloff, Xenia F.
    Herter, Sonja
    Fiesel, Petra
    Berker, Yannick
    Blattner-Johnson, Mirjam
    Schramm, Kathrin
    Jones, Barbara C.
    Reuss, David
    Turunen, Laura
    Friedenauer, Aileen
    Holland-Letz, Tim
    Sill, Martin
    Weiser, Lena
    Previti, Christopher
    Balasubramanian, Gnanaprakash
    Gerber, Nicolas U.
    Gojo, Johannes
    Hutter, Caroline
    Ora, Ingrid
    Lohi, Olli
    Kattamis, Antonis
    de Wilde, Bram
    Westermann, Frank
    Tippelt, Stephan
    Graf, Norbert
    Nathrath, Michaela
    Sparber-Sauer, Monika
    Sehested, Astrid
    Kramm, Christof M.
    Dirksen, Uta
    Kallioniemi, Olli
    Pfister, Stefan M.
    van Tilburg, Cornelis M.
    Jones, David T. W.
    Saarela, Jani
    Pietiaeinen, Vilja
    Jaeger, Natalie
    Schlesner, Matthias
    Kopp-Schneider, Annette
    Oppermann, Sina
    Milde, Till
    Witt, Olaf
    Oehme, Ina
    [J]. NPJ PRECISION ONCOLOGY, 2022, 6 (01)
  • [35] Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM
    Heike Peterziel
    Nora Jamaladdin
    Dina ElHarouni
    Xenia F. Gerloff
    Sonja Herter
    Petra Fiesel
    Yannick Berker
    Mirjam Blattner-Johnson
    Kathrin Schramm
    Barbara C. Jones
    David Reuss
    Laura Turunen
    Aileen Friedenauer
    Tim Holland-Letz
    Martin Sill
    Lena Weiser
    Christopher Previti
    Gnanaprakash Balasubramanian
    Nicolas U. Gerber
    Johannes Gojo
    Caroline Hutter
    Ingrid Øra
    Olli Lohi
    Antonis Kattamis
    Bram de Wilde
    Frank Westermann
    Stephan Tippelt
    Norbert Graf
    Michaela Nathrath
    Monika Sparber-Sauer
    Astrid Sehested
    Christof M. Kramm
    Uta Dirksen
    Olli Kallioniemi
    Stefan M. Pfister
    Cornelis M. van Tilburg
    David T. W. Jones
    Jani Saarela
    Vilja Pietiäinen
    Natalie Jäger
    Matthias Schlesner
    Annette Kopp-Schneider
    Sina Oppermann
    Till Milde
    Olaf Witt
    Ina Oehme
    [J]. npj Precision Oncology, 6
  • [36] Novel therapeutic possibilities for chemorefractory ovarian cancer patients identified by functional ex vivo drug sensitivity testing of primary cells
    Murumagi, A.
    Hirasawa, A.
    Khan, S.
    Arjama, M.
    Pellinen, T.
    Koivisto-Korander, R.
    Leminen, A.
    Magi, A.
    Aittokallio, T.
    Butzow, R.
    Kallioniemi, O.
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2016, 26 : 653 - 653
  • [37] Determining Tumor Heterogeneity and Response to Treatment Ex Vivo Using 3D Mammosphere Cultures Derived from Primary Breast Cancers and Metastases
    Gilmore, H. L.
    Miskimen, K.
    Difeo, A.
    Harris, L. N.
    [J]. LABORATORY INVESTIGATION, 2013, 93 : 43A - 43A
  • [38] Determining Tumor Heterogeneity and Response to Treatment Ex Vivo Using 3D Mammosphere Cultures Derived from Primary Breast Cancers and Metastases
    Gilmore, H. L.
    Miskimen, K.
    Difeo, A.
    Harris, L. N.
    [J]. MODERN PATHOLOGY, 2013, 26 : 43A - 43A
  • [39] A unique ex vivo tumor model: 3D co-cultured system with cancer cells and stromal tissue for drug evaluation
    Takahashi, Yuki
    Tsukamoto, Kei
    Shimizu, Yuki
    Katayama, Ryohei
    Shinozaki, Eiji
    Nagayama, Satoshi
    Matsusaki, Michiya
    Kitano, Shiro
    Yamaguchi, Kensei
    Fujita, Naoya
    [J]. CANCER RESEARCH, 2020, 80 (16)
  • [40] Ex vivo breast tumors for understanding the patient specific tumor microenvironment remodeling and drug responses
    Martin, Elizabeth
    Benz, Megan
    Hebert, Katie
    Byrne, Ethan
    Lau, Frank
    [J]. CANCER RESEARCH, 2024, 84 (06)
12345