Second transplantation with CD34+ blood cells from an HLA-mismatched related donor after engraftment failure of transplanted cord blood cells

被引:0
|
作者
Ohta, H [1 ]
Kim, JY [1 ]
Sawada, A [1 ]
Tokimasa, S [1 ]
Fujisaki, H [1 ]
Matsuda, Y [1 ]
Osugi, Y [1 ]
Hara, J [1 ]
机构
[1] Osaka Univ, Grad Sch Med, Dept Dev Med Pediat, Suita, Osaka 5650871, Japan
关键词
second transplantation; CD34(+) blood cells; engraftment failure; cord blood transplantation;
D O I
10.1007/BF02982071
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Unrelated cord blood transplantation (CBT) has been worldwide for bone marrow reconstitution. CBT is associated with a high frequency of engraftment failure and rejection due to a small dose of graft cells. In cases of engraftment failure or rejection following unrelated CBT retransplantation from the original donors is impossible. We report a successful transplantation with CD34(+) blood cells selected from a 2-loci HLA-mismatched mother to a child with acute monocytic leukemia after engraftment failure of the primary CBT. Selected CD34(+) blood cell transplantation is a useful approach for retransplantation in the setting of engraftment failure. (C) 2001 The Japanese Society of Hematology.
引用
收藏
页码:338 / 341
页数:4
相关论文
共 50 条
  • [21] Allogeneic peripheral stem cell transplantation using positively selected CD34+ cells from HLA-mismatched donors
    Matsuda, Y
    Hara, J
    Osugi, Y
    Fujisaki, H
    Takai, K
    Ohta, H
    Nakanishi, K
    Tokimasa, S
    Miyoshi, H
    Tanaka-Taya, K
    Yamanishi, K
    Okada, S
    [J]. BONE MARROW TRANSPLANTATION, 1998, 21 (04) : 355 - 360
  • [22] Allogeneic peripheral stem cell transplantation using positively selected CD34+ cells from HLA-mismatched donors
    Y Matsuda
    J Hara
    Y Osugi
    H Fujisaki
    K Takai
    H Ohta
    K Nakanishi
    S Tokimasa
    H Miyoshi
    K Tanaka-Taya
    K Yamanishi
    S Okada
    [J]. Bone Marrow Transplantation, 1998, 21 : 355 - 360
  • [23] Cord blood transplants supported by unrelated donor CD34+ progenitor cells
    Alexandra Gomez-Arteaga
    Nina Orfali
    Danielle Guarneri
    Melissa M. Cushing
    Usama Gergis
    Jingmei Hsu
    Yen-Michael S. Hsu
    Sebastian A. Mayer
    Adrienne A. Phillips
    Stacy A. Chase
    Asmaa E. Mokhtar
    Tsiporah B. Shore
    Koen Van Besien
    [J]. Bone Marrow Transplantation, 2020, 55 : 2298 - 2307
  • [24] Recovery and characterization of CD34+ cord blood cells after cryopreservation
    Lu, L
    Li, ZH
    Broxmeyer, HE
    [J]. IN VIVO, 1996, 10 (02): : 229 - 232
  • [25] Demonstration of long-term engraftment of donor CD34+ HLA-DR. bone marrow cells after allogeneic peripheral blood transplantation.
    Briones, J
    Urbano-Ispizua, A
    Orfao, A
    Marin, P
    Sierra, J
    Rovira, M
    Carreras, E
    Rozman, C
    Montserrat, E
    [J]. BONE MARROW TRANSPLANTATION, 1998, 21 : S104 - S104
  • [26] Kinetics of engraftment of CD34- and CD34+ cells from mobilized blood differs from that of CD34- and CD34+ cells from bone marrow
    Verfaillie, CM
    Almeida-Porada, G
    Wissink, S
    Zanjani, ED
    [J]. EXPERIMENTAL HEMATOLOGY, 2000, 28 (09) : 1071 - 1079
  • [27] Delayed engraftment of NOD/SCID mice transplanted with ex vivo expanded human CD34+ cord blood cells.
    Güenechea, G
    Segovia, JC
    Albella, B
    Lamana, M
    Ramírez, M
    Regidor, C
    Fernández, MN
    Bueren, JA
    [J]. BONE MARROW TRANSPLANTATION, 1999, 23 : S199 - S199
  • [28] Early monitoring of engraftment and rejection after transplantation of highly purified peripheral blood CD34+ cells.
    Peters, C
    Matthes-Martin, S
    Fritsch, G
    Lion, T
    Höcker, P
    Gadner, H
    [J]. BONE MARROW TRANSPLANTATION, 1999, 23 : S144 - S144
  • [29] Partially mismatched pediatric transplants with allogeneic CD34+ blood cells from related donors.
    Takaue, Y
    Kawano, Y
    Watanabe, A
    Arai, K
    Ito, E
    Teshima, T
    Kuroda, Y
    Asano, S
    McMannis, JD
    [J]. BLOOD, 1996, 88 (10) : 1061 - 1061
  • [30] Competitive engraftment potential of primary and ex vivo expanded cord blood CD34+cells in a triple HLA-mismatched SCID-hu bone model.
    Rosler, ES
    Brandt, JE
    Chute, J
    Hoffman, R
    [J]. BLOOD, 1999, 94 (10) : 706A - 706A