Two new cadinane-type sesquiterpenoid glycosides from Dryopteris fragrans with anti-inflammatory activities

被引：1
|
作者：
Peng, Bing [1 ,2 ]
Han, Xu-Yang [1 ,2 ]
Wang, Hong [1 ,2 ]
Zhang, Wen-Jing [1 ,2 ]
Zeng, Zu-Ping [1 ,2 ]
机构：
[1] Capital Med Univ, Beijing Inst Chinese Med, Beijing Hosp Tradit Chinese Med, Beijing 100010, Peoples R China
[2] Beijing Key Lab Clin & Basic Res Tradit Chinese M, Beijing 100010, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2022年 / 24卷 / 11期
基金：
北京市自然科学基金;
关键词：
Dryopteris fragrans; Dryopteridaceae; cadinane sesquiterpenoid; dryopteristerpene A; dryopteristerpene B; anti-inflammatory activity;
D O I：
10.1080/10286020.2022.2028776
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new cadinane-type sesquiterpenoid glycosides, dryopteristerpeneA (1) and dryopteristerpeneB (2), were isolated from the aqueous extract of Dryopterisfragrans. Their structures were determined by spectroscopic data analysis and electronic circular dichroism (ECD) calculations.Compounds 1 and 2 exhibited inhibition on nitric oxide production in lipopolysaccharide induced RAW 264.7 macrophages with their IC50 values of 60.5 and 59.8 mu M, respectively.
引用
收藏
页码：1064 / 1070
页数：7
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