Multiple functions of mouse zona pellucida glycoprotein mZP3, the sperm receptor

被引:0
|
作者
Wassarman, PM [1 ]
Litscher, ES [1 ]
机构
[1] CUNY Mt Sinai Sch Med, Dept Biochem & Mol Biol, New York, NY 10029 USA
关键词
oogenesis; fertilization; zona pellucida; mZP3; sperm receptor; acrosome reaction-inducer;
D O I
暂无
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Zona pellucida glycoprotein mZP3 is a structural glycoprotein, a sperm receptor, and an acrosome reaction-inducer. The latter two functions are mediated, at least in part, by mZP3 oligosaccharides. mZP3 is unique to mammalian eggs, from mice to humans, although related glycoproteins are found in vitelline envelopes of a variety of eggs, from fish to birds.
引用
收藏
页码:21 / 32
页数:12
相关论文
共 50 条
  • [21] Identification of epitopes of monoclonal antibodies to porcine zona pellucida 3 beta glycoprotein, a homologue of the mouse/human sperm receptor
    Afzalpurkar, A
    Gupta, SK
    AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 1997, 38 (01): : 26 - 32
  • [22] Inactivation of the mouse sperm receptor, mZP3, by site-directed mutagenesis of individual serine residues located at the combining site for sperm
    Chen, J
    Litscher, ES
    Wassarman, PM
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (11) : 6193 - 6197
  • [23] Sperm arylsulfatase A binds to mZP2 and mZP3 glycoproteins in a nonenzymatic manner
    Xu, Hongbin
    Liu, Fang
    Srakaew, Nopparat
    Koppisetty, Chaitanya
    Nyholm, Per-Georg
    Carmona, Euridice
    Tanphaichitr, Nongnuj
    REPRODUCTION, 2012, 144 (02) : 209 - 219
  • [24] A MOUSE OOCYTE-SPECIFIC PROTEIN THAT BINDS TO A REGION OF MZP3 PROMOTER RESPONSIBLE FOR OOCYTE-SPECIFIC MZP3 GENE-EXPRESSION
    SCHICKLER, M
    LIRA, SA
    KINLOCH, RA
    WASSARMAN, PM
    MOLECULAR AND CELLULAR BIOLOGY, 1992, 12 (01) : 120 - 127
  • [25] Human sperm surface glycoprotein involved in sperm zona pellucida interaction
    Batova, IN
    Ivanova, MD
    Mollova, MV
    Kyurkchiev, SD
    INTERNATIONAL JOURNAL OF ANDROLOGY, 1998, 21 (03): : 141 - 153
  • [26] Equine sperm surface galactosyltransferase and zona glycoprotein ZPC are not necessary for sperm binding to the zona pellucida
    Mugnier, S.
    Lahuec, C.
    Yvon, J. M.
    Magistrini, M.
    Goudet, G.
    ANIMAL REPRODUCTION SCIENCE, 2006, 94 (1-4) : 331 - 332
  • [27] Conversion of Ser to Thr residues at the sperm combining-site of mZP3 does not affect sperm receptor activity
    Williams, Z
    Litscher, ES
    Wassarman, PM
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 301 (04) : 813 - 818
  • [28] SPERM EGG INTERACTIONS IN THE MOUSE - SEQUENCE OF EVENTS AND INDUCTION OF THE ACROSOME REACTION BY A ZONA PELLUCIDA GLYCOPROTEIN
    BLEIL, JD
    WASSARMAN, PM
    DEVELOPMENTAL BIOLOGY, 1983, 95 (02) : 317 - 324
  • [29] COLD LABILITY OF MOUSE SPERM BINDING TO ZONA PELLUCIDA
    HEFFNER, LJ
    STOREY, BT
    JOURNAL OF EXPERIMENTAL ZOOLOGY, 1982, 219 (02): : 155 - 161
  • [30] MOUSE SPERM REQUIRE CALCIUM TO BIND TO ZONA PELLUCIDA
    SALING, PM
    STOREY, BT
    WOLF, DP
    FEDERATION PROCEEDINGS, 1977, 36 (03) : 811 - 811