The 2-(allyloxy) phenyl acetyl ester as a new relay protecting group for oligosaccharide synthesis

被引：16

作者：

Arranz, E ^{[1
]}

Boons, GJ ^{[1
]}

机构：

[1] Univ Georgia, Complex Carbohydrate Res Ctr, Athens, GA 30602 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 37期

关键词：

D O I：

10.1016/S0040-4039(01)01303-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 2-(allyloxy) phenyl acetyl group can be removed by a relay approach using Pd(PPh3)(4) in combination with proton sponge, conditions that do not affect acetyl, benzoyl and levulinoyl esters. On the other hand, the acetyl and levulinoyl ester could be cleaved without removal of the 2-(allyloxy) phenyl acetyl group. The new protecting group is compatible with glycosylations and can perform efficiently neighboring group participation leading to the exclusive formation of 1,2-trans glycosides. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：6469 / 6471

页数：3

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