EBV-specific CD8+T cells are exhausted and senescent in multiple sclerosis patients

被引:0
|
作者
Angelini, D. F. [1 ]
Guerrera, G. [1 ]
Ruggieri, S. [2 ,3 ]
Gargano, F. [1 ]
Placido, R. [1 ]
Borsellino, G. [1 ]
Battistini, L. [1 ]
Gasperini, C. [2 ]
机构
[1] Fdn Santa Lucia, Neuroimmunol Unit, Rome, Italy
[2] AO S Camillo Forlanini, Dept Neurosci, Rome, Italy
[3] Univ Rome Sapienza, Dept Neurol & Psichiat, Rome, Italy
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
P425
引用
收藏
页码:177 / 177
页数:1
相关论文
共 50 条
  • [21] EBNA1 antigen-specific CD8+T cells in cerebrospinal fluid of patients with multiple sclerosis
    Erdur, Hebun
    Scholz, Veronika
    Streitz, Mathias
    Hammer, Markus
    Meisel, Christian
    Schoenemann, Constanze
    Wandinger, Klaus-Peter
    Rosche, Berit
    JOURNAL OF NEUROIMMUNOLOGY, 2016, 294 : 14 - 17
  • [22] EBV-Specific CD8+ T Cells from Asymptomatic Pediatric Thoracic Transplant Patients Carrying Chronic High EBV Loads Display Contrasting Features: Activated Phenotype and Exhausted Function
    Macedo, Camila
    Webber, Steven A.
    Donnenberg, Albert D.
    Popescu, Iulia
    Hua, Yun
    Green, Michael
    Rowe, David
    Smith, Louise
    Brooks, Maria M.
    Metes, Diana
    JOURNAL OF IMMUNOLOGY, 2011, 186 (10): : 5854 - 5862
  • [23] EBV-Specific CD8+ T-Cells Are Not Functionally Impaired in Chronic Lymphocytic Leukemia
    Hofland, Tom
    de Weerdt, Iris
    Terpstra, Sanne
    Remmerswaal, Ester B. M.
    ten Berge, Ineke J. M.
    Kater, Arnon P.
    Tonino, Sanne H.
    BLOOD, 2015, 126 (23)
  • [24] EBV-specific immune responses in patients with multiple sclerosis responding to IFNβ therapy
    Comabella, Manuel
    Kakalacheva, Kristina
    Rio, Jordi
    Muenz, Christian
    Montalban, Xavier
    Luenemann, Jan D.
    MULTIPLE SCLEROSIS JOURNAL, 2012, 18 (05) : 605 - 609
  • [25] Antitumor CD8+T Cells in Hepatocellular Carcinoma: Present but Exhausted
    Li, Ka-Kit
    Adams, David H.
    HEPATOLOGY, 2014, 59 (04) : 1232 - 1234
  • [26] Exhausted CD8+T cells face a developmental fork in the road
    Zander, Ryan
    Cui, Weiguo
    TRENDS IN IMMUNOLOGY, 2023, 44 (04) : 276 - 286
  • [27] CD8+T Cells Exhibit an Exhausted Phenotype in Hemophagocytic Lymphohistiocytosis
    Kelkar, Madhura G.
    Bargir, Umair Ahmad
    Malik-Yadav, Reetika
    Gupta, Maya
    Dalvi, Aparna
    Jodhawat, Neha
    Shinde, Shweta
    Madkaikar, Manisha R.
    JOURNAL OF CLINICAL IMMUNOLOGY, 2021, 41 (08) : 1794 - 1803
  • [28] EBV-specific CD8+ T cell reactivation in transplant patients results in expansion of CD8+ type-1 regulatory T cells
    Popescu, I.
    Macedo, C.
    Abu-Elmagd, K.
    Shapiro, R.
    Hua, Y.
    Thomson, A. W.
    Morelli, A. E.
    Storkus, W. J.
    Metes, D.
    AMERICAN JOURNAL OF TRANSPLANTATION, 2007, 7 (05) : 1215 - 1223
  • [29] Tailored immunotherapy with EBV-specific T cells
    Krome, Susanne
    TRANSFUSIONSMEDIZIN, 2023, 13 (04) : 178 - 179
  • [30] Characterization of Myelin-reactive CD8+T cells in Multiple Sclerosis
    Sabatino, Joseph
    Wilson, Michael
    Calabresi, Peter
    Hauser, Stephen
    Schneck, Jonathan
    Zamvil, Scott
    NEUROLOGY, 2019, 92 (15)