Ten-year trends in benzodiazepine use in the Dutch population

被引:61
|
作者
Sonnenberg, Caroline M. [1 ]
Bierman, Ellis J. M. [1 ]
Deeg, Dorly J. H. [1 ]
Comijs, Hannie C. [1 ]
van Tilburg, Willem [1 ]
Beekman, Aartjan T. F. [1 ]
机构
[1] Vrije Univ Amsterdam, Med Ctr, Dept Psychiat, VU Med Ctr,Inst Res Extramural Med EMGO, NL-1075 BH Amsterdam, Netherlands
关键词
Benzodiazepine use; Time trends; Population; Ageing; CHRONIC DISEASES; SEX-DIFFERENCES; OLDER-ADULTS; DEPRESSION; PATTERNS; RISK; PREVALENCE; EPIDEMIOLOGY; DETERMINANTS; PERSPECTIVES;
D O I
10.1007/s00127-011-0344-1
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
In the past decades knowledge on adequate treatment of affective disorders and awareness of the negative consequences of long-term benzodiazepine use increased. Therefore, a decrease in benzodiazepine use is expected, particularly in prolonged use. The aim of this study was to assess time trends in benzodiazepine use. Data from the Longitudinal Aging Study Amsterdam (LASA) were used to investigate trends in benzodiazepine use between 1992 and 2002 in two population-based samples aged 55-64 years. Differences between the two samples with respect to benzodiazepine use and to sociodemographic, physical health and mental health characteristics were described and tested with chi-square tests and logistic regression analyses. Benzodiazepine use remained stable over 10 years, with 7.8% in LASA-1 (n = 874) and 7.9% in LASA-2 (n = 919) (p = 0.90) with a persisting preponderance in women and in people with low education, low income, chronic physical diseases, functional limitations, cognitive impairment, depression, anxiety complaints, sleep problems and when using antidepressants. Long-term use remained high with 70% in 1992 and 80% in 2002 of total benzodiazepine use. In the Dutch population aged 55-64, overall benzodiazepine use remained stable from 1992 to 2002, with a high proportion of long-term users, despite the effort to reduce benzodiazepine use and the renewal of the guidelines. More effort should be made to decrease prolonged benzodiazepine use in this middle-aged group, because of the increasing risks with ageing.
引用
收藏
页码:293 / 301
页数:9
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