RAF around the Edges - The Paradox of BRAF Inhibitors

被引：35
|
作者：
Weeraratna, Ashani T. [1 ]
机构：
[1] Wistar Inst Anat & Biol, Mol & Cellular Oncogenesis Program, Philadelphia, PA 19104 USA
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2012年 / 366卷 / 03期
关键词：
RESISTANCE; MELANOMA;
D O I：
10.1056/NEJMe1111636
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：271 / 273
页数：3
相关论文
共 50 条
  • [31] Innovating around the edges
    Depalma, Angelo (angelo@adepalma.com), 1600, LabX Media Group (07):
  • [32] Reading around the Edges
    Medland, Bill
    IEEE SOFTWARE, 2010, 27 (01) : 9 - 9
  • [33] Emerging Raf inhibitors
    McCubrey, James A.
    Steelman, Linda S.
    Abrams, Steven L.
    Chappell, William H.
    Russo, Suzanne
    Ove, Roger
    Milella, Michele
    Tafuri, Agostino
    Lunghi, Paolo
    Bonati, Antonio
    Stivala, Franca
    Nicoletti, Ferdinando
    Libra, Massimo
    Martelli, Alberto M.
    Montalto, Giuseppe
    Cervello, Melchiorre
    EXPERT OPINION ON EMERGING DRUGS, 2009, 14 (04) : 633 - 648
  • [34] Raf kinase inhibitors
    不详
    EXPERT OPINION ON THERAPEUTIC PATENTS, 1998, 8 (12) : 1749 - 1750
  • [35] TYPE II RAF INHIBITORS INHIBIT BRAF MUTATIONS AND TRUNCATED FUSIONS IN PEDIATRIC LOW-GRADE GLIOMAS
    Kieran, Mark W.
    Sun, Yu
    Pilarz, Catherine
    Calligaris, David
    Chadwick, Emily J.
    Alberta, John A.
    Ramkissoon, Shakti H.
    Ramkissoon, Lori A.
    Garcia, Veronica Matia
    Wilkinson, Kim
    Kane, Michael
    Goumnerova, Liliana
    Chi, Susan N.
    Manley, Peter
    Wright, Karen D.
    Agar, Nathalie Y.
    Ligon, Keith L.
    Beroukhim, Rameen
    Bandopadhayay, Pratiti
    Kannan, Geoffrey
    Segal, Rosalind A.
    Garraway, Levi A.
    Gray, Nathanael S.
    Eck, Michael
    Stiles, Charles D.
    Buhrlage, Sara J.
    NEURO-ONCOLOGY, 2016, 18 : 89 - 89
  • [36] BRAF Gene Fusions Occur Across a Diverse Subset of Human Solid Tumors and Respond To RAF Kinase Inhibitors
    Ross, Jeffrey
    Wang, Kai
    Chmielecki, Juliann
    Ali, Siraj
    Elvin, Julia
    Yelensky, Roman
    Lipson, Doron
    Millet, Vincent
    Stephens, Philip
    MODERN PATHOLOGY, 2015, 28 : 462A - 462A
  • [37] BRAF Gene Fusions Occur Across a Diverse Subset of Human Solid Tumors and Respond To RAF Kinase Inhibitors
    Ross, Jeffrey
    Wang, Kai
    Chmielecki, Juliann
    Ali, Siraj
    Elvin, Julia
    Yelensky, Roman
    Lipson, Doron
    Miller, Vincent
    Stephens, Philip
    LABORATORY INVESTIGATION, 2015, 95 : 462A - 462A
  • [38] Novel oncogenic BRaf deletions functioning as BRaf homodimer and sensitive to inhibition by LY3009120, a pan Raf and Raf dimer inhibitor
    Chen, Shih-Hsun
    Buchanan, Sean
    Zhang, Youyan
    Van Horn, Robert
    Yin, Tinggui
    Yadav, Vipin
    Wong, Swee Seong
    Huber, Lysiane
    Henry, James
    Conti, Ilaria
    Starling, James J.
    Plowman, Gregory D.
    Peng, Sheng-Bin
    CANCER RESEARCH, 2015, 75
  • [39] Breaking the paradox breakers - RAF inhibitor mechanisms
    Mendiratta, Gaurav
    McFall, Thomas
    Stites, Edward
    CANCER RESEARCH, 2020, 80 (16)
  • [40] Radiosensitization by BRAF inhibitors
    Strobel, Sophia Boyoung
    Paetzold, Sylvie
    Zimmer, Lisa
    Jensen, Alexandra
    Enk, Alexander
    Hassel, Jessica Cecile
    JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2017, 15 (07): : 703 - 708
12345