Infusion of a physiological dose of leucine stimulates muscle protein synthesis in neonatal pigs by enhancing the activity of translation initiation factors

被引:0
|
作者
Escobar, J. [1 ]
Frank, J. W. [1 ]
Kimball, S. R. [2 ]
Suryawan, A. [1 ]
Nguyen, H. V. [1 ]
Liu, C. W. [1 ]
Jefferson, L. S. [2 ]
Davis, T. A. [1 ]
机构
[1] Baylor Coll Med, Childrens Nutr Res Ctr, USDA ARS, Houston, TX 77030 USA
[2] Penn State Univ, Coll Med, Hershey, PA USA
关键词
leucine; translation initiation factors; protein synthesis;
D O I
暂无
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
引用
收藏
页码:419 / 419
页数:1
相关论文
共 50 条
  • [41] Prematurity blunts the insulin- and amino acid-induced stimulation of translation initiation and protein synthesis in skeletal muscle of neonatal pigs
    Rudar, Marko
    Naberhuis, Jane K.
    Suryawan, Agus
    Nguyen, Hanh, V
    Stoll, Barbara
    Style, Candace C.
    Verla, Mariatu A.
    Olutoye, Oluyinka O.
    Burrin, Douglas G.
    Fiorotto, Marta L.
    Davis, Teresa A.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2021, 320 (03): : E551 - E565
  • [42] Endotoxin Reduces Muscle Protein Synthesis and Restrains Translation Initiation by Decreasing eIF4G Phosphorylation in Neonatal and Young Pigs
    Orellana, Renan
    Gazzaneo, Maria Carolina
    Wilson, Fiona
    Nguyen, Hanh V.
    Suryawan, Agus
    Davis, Teresa A.
    FASEB JOURNAL, 2008, 22
  • [43] Amino acids augment muscle protein synthesis in neonatal pigs during acute endotoxemia by stimulating mTOR-dependent translation initiation
    Orellana, Renan A.
    Jeyapalan, Asumthia
    Escobar, Jeffery
    Frank, Jason W.
    Nguyen, Hanh V.
    Suryawan, Agus
    Davis, Teresa A.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2007, 293 (05): : E1416 - E1425
  • [44] Feeding stimulates protein synthesis in muscle and liver of neonatal pigs through an mTOR-dependent process
    Kimball, SR
    Jefferson, LS
    Nguyen, HV
    Suryawan, A
    Bush, JA
    Davis, TA
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2000, 279 (05): : E1080 - E1087
  • [45] Effect of different leucine supplementation in low protein diet on Protein Synthesis and Activation of Translation Initiation Factors of Weaned Piglets
    Yin, Yulong
    Wu, Guoyao
    Liu, Zhaojin
    Chu, Wuyin
    Huang, Ruilin
    Li, Tiejun
    Hou, Rongqing
    Liu, Yulan
    FASEB JOURNAL, 2008, 22
  • [46] Leucine supplementation stimulates protein synthesis and reduces degradation signal activation in muscle of newborn pigs during acute endotoxemia
    Hernandez-Garcia, Adriana D.
    Columbus, Daniel A.
    Manjarin, Rodrigo
    Nguyen, Hanh V.
    Suryawan, Agus
    Orellana, Renan A.
    Davis, Teresa A.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2016, 311 (04): : E791 - E801
  • [47] Leucine supplementation of a chronically restricted protein and energy diet enhances mTOR pathway activation but not muscle protein synthesis in neonatal pigs
    Rodrigo Manjarín
    Daniel A. Columbus
    Agus Suryawan
    Hanh V. Nguyen
    Adriana D. Hernandez-García
    Nguyet-Minh Hoang
    Marta L. Fiorotto
    Teresa Davis
    Amino Acids, 2016, 48 : 257 - 267
  • [48] Leucine Supplementation of a Protein and Energy Restricted Diet Enhances mTORC1 Activation but not Protein Synthesis in Muscle of Neonatal Pigs
    Manjarin, Rodrigo
    Columbus, Daniel
    Suryawan, Agus
    Hernandez-Garcia, Adriana
    Nguyen, Hanh
    Fiorotto, Marta
    Hoang, Nguyet-Minh
    Davis, Teresa
    FASEB JOURNAL, 2015, 29
  • [49] Effect of Prolonged Enteral Leucine Supplementation on Muscle Protein Synthesis and mTOR Activation in Neonatal Pigs Fed a Restricted Protein Diet
    Columbus, Daniel
    Steinhoff-Wagner, Julia
    Suryawan, Agus
    Nguyen, Hanh
    Hernandez-Garcia, Adriana
    Fiorotto, Marta
    Davis, Teresa
    FASEB JOURNAL, 2015, 29
  • [50] Leucine supplementation of a chronically restricted protein and energy diet enhances mTOR pathway activation but not muscle protein synthesis in neonatal pigs
    Manjarin, Rodrigo
    Columbus, Daniel A.
    Suryawan, Agus
    Nguyen, Hanh V.
    Hernandez-Garcia, Adriana D.
    Nguyet-Minh Hoang
    Fiorotto, Marta L.
    Davis, Teresa
    AMINO ACIDS, 2016, 48 (01) : 257 - 267