Highly similar noncoding genomic DNA sequences: ultraconserved, or merely widespread?

被引：2
|
作者：
Hickey, Donal A. [1 ]
机构：
[1] Concordia Univ, Dept Biol, Montreal, PQ H4B 1R6, Canada
来源：
GENOME | 2008年 / 51卷 / 05期
关键词：
transposon; mobile genetic element; human genome; nongenic;
D O I：
10.1139/G08-011
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In this note, I propose an explanation for the seeming contradiction between bioinformatics-based predictions of an essential function for ultraconserved DNA sequences, and the lack of an experimental demonstration of such function.
引用
收藏
页码：396 / 397
页数：2
相关论文
共 50 条
  • [21] FRESCO: Referential Compression of Highly Similar Sequences
    Wandelt, Sebastian
    Leser, Ulf
    IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 2013, 10 (05) : 1275 - 1288
  • [22] Analysis of the genomic DNA of the harmful dinoflagellate Prorocentrum minimum: a brief survey focused on the noncoding RNA gene sequences
    Ponmani, Thangaraj
    Guo, Ruoyu
    Ki, Jang-Seu
    JOURNAL OF APPLIED PHYCOLOGY, 2016, 28 (01) : 335 - 344
  • [23] Analysis of the genomic DNA of the harmful dinoflagellate Prorocentrum minimum: a brief survey focused on the noncoding RNA gene sequences
    Thangaraj Ponmani
    Ruoyu Guo
    Jang-Seu Ki
    Journal of Applied Phycology, 2016, 28 : 335 - 344
  • [24] Toward Identification of Functional Sequences and Variants in Noncoding DNA
    Monti, Remo
    Ohler, Uwe
    ANNUAL REVIEW OF BIOMEDICAL DATA SCIENCE, 2023, 6 : 191 - 210
  • [25] Methylated DNA sequences in genomic imprinting
    Mann, JR
    Szabó, PE
    Reed, MR
    Singer-Sam, J
    CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION, 2000, 10 (3-4): : 241 - 257
  • [26] Levels of ordering in coding and noncoding regions of DNA sequences
    Chechetkin, VR
    Lobzin, VV
    PHYSICS LETTERS A, 1996, 222 (05) : 354 - 360
  • [27] Clustering of identical oligomers in coding and noncoding DNA sequences
    Stanley, RHR
    Dokholyan, NV
    Buldyrev, SV
    Havlin, S
    Stanley, HE
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1999, 17 (01): : 79 - 87
  • [28] Levels of ordering in coding and noncoding regions of DNA sequences
    Phys Lett Sect A Gen At Solid State Phys, 5 (354):
  • [29] Inconsistencies in Neanderthal genomic DNA sequences
    Wall, Jeffrey D.
    Kim, Sung K.
    PLOS GENETICS, 2007, 3 (10): : 1862 - 1866
  • [30] Which are more random: Coding or noncoding DNA sequences?
    Wu, F
    Zheng, WM
    COMMUNICATIONS IN THEORETICAL PHYSICS, 2002, 37 (05) : 637 - 640
12345