Anesthesia: Synaptic power failure

被引：2
|
作者：
van Swinderen, Bruno [1 ]
Kelz, Max B. [2 ]
机构：
[1] Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia
[2] Univ Penn, Perelman Sch Med, Dept Anesthesiol & Crit Care, Philadelphia, PA 19104 USA
来源：
CURRENT BIOLOGY | 2022年 / 32卷 / 14期
关键词：
VOLATILE-ANESTHETICS; GENERAL-ANESTHESIA; SENSITIVITY; SLEEP;
D O I：
10.1016/j.cub.2022.06.043
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
One of the greatest unresolved mysteries in medicine relates to the molecular and neuronal mechanisms through which general anesthetics abolish perception. A new study in mice with mutations affecting mitochondrial complex 1 suggests that anesthetic-disruption of cellular energetics impairs endocytosis to alter synaptic function.
引用
收藏
页码：R781 / R783
页数：3
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