Rapid intrahepatic and peripheral blood HCV RNA decline and HCV-specific immune response increase during IFN-free DAA therapy in HCV treatment-naive patients

被引:0
|
作者
MacParland, Sonya A. [1 ,2 ]
Cherepanov, Vera [1 ,2 ]
Vijgen, Leen [4 ]
Gamil, Mohamed [4 ]
Beumont, Maria [4 ]
Yoon, Sharon [1 ]
Rahman, A. K. M. Nur-Ur [1 ]
Aquino, Analiza [5 ]
Capraru, Camelia [2 ]
Brahmania, Mayur [1 ]
Ostrowski, Mario [1 ]
Wong, David K. [2 ]
Janssen, Harry L. [2 ]
Sulkowski, Mark S. [3 ]
Feid, Jordan J. [1 ,2 ]
机构
[1] Univ Toronto, Toronto, ON, Canada
[2] McLaughlin Rotman Ctr Global Hlth, Toronto Ctr Liver Dis, Toronto, ON, Canada
[3] Johns Hopkins Univ, Sch Med, Bethesda, MD USA
[4] Janssen Infect Dis BVBA, Beerse, Belgium
[5] Mt Sinai Hosp, Toronto, ON, Canada
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
1465
引用
收藏
页码:732A / 732A
页数:1
相关论文
共 50 条
  • [21] Quality of Life for HCV-infected Patients during Treatment: Are IFN-free Better than IFN-based Regimens?
    Nickerson, Jillian
    Bichoupan, Kian
    Harty, Alyson
    Weiss, Jeffrey J.
    Perumalswami, Ponni
    Schiano, Thomas D.
    Dieterich, Douglas
    Branch, Andrea D.
    HEPATOLOGY, 2014, 60 : 693A - 693A
  • [22] Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy
    Burchill, Matthew A.
    Roby, Justin A.
    Crochet, Nanette
    Wind-Rotolo, Megan
    Stone, Amy E.
    Edwards, Michael G.
    Dran, Rachael J.
    Kriss, Michael S.
    Gale, Michael, Jr.
    Rosen, Hugo R.
    PLOS ONE, 2017, 12 (10):
  • [23] Efficacy and safety of IFN-free DAA therapy in HIV/HCV co-infected patients: Results from a pan-European study
    Peters, L.
    Lundgren, J. D.
    Rockstroh, J.
    Mocroft, A.
    JOURNAL OF HEPATOLOGY, 2018, 68 : S268 - S268
  • [24] Shortened treatment duration in treatment-naive genotype 1 HCV patients with rapid virological response: A meta-analysis
    Moreno, Christophe
    Deltenre, Pierre
    Pawlotsky, Jean-Michel
    Henrion, Jean
    Adler, Michael
    Mathurin, Philippe
    JOURNAL OF HEPATOLOGY, 2010, 52 (01) : 25 - 31
  • [25] IFN-free DAA regimens improve on-treatment quality of life in patients with HIV/HCV coinfection in contrast to previously used PEGIFN/RBV regimens
    Scheiner, Bernhard
    Schwabl, Philipp
    Mandorfer, Mattias
    Steiner, Sebastian
    Chromy, David
    Bucsics, Theresa
    Payer, Berit A.
    Aichelburg, Maximilian C.
    Rieger, Armin
    Grabmeier-Pfistershammer, Katharina
    Trauner, Michael
    Peck-Ra-Dosavljevic, Markus
    Reiberger, Thomas
    HEPATOLOGY, 2015, 62 : 805A - 806A
  • [26] Presence of hepatitis C virus (HCV)-RNA in peripheral blood mononuclear cells in HCV serum negative patients during interferon and ribavirin therapy
    Januszkiewicz-Lewandowska, Danuta
    Wysocki, Jacek
    Pernak, Monika
    Nowicka, Kanina
    Zawada, Mariola
    Rembowska, Jolanta
    Lewandowski, Krzysztof
    Mankowski, Przemyslaw
    Nowak, Jerzy
    JAPANESE JOURNAL OF INFECTIOUS DISEASES, 2007, 60 (01) : 29 - 32
  • [27] EXPOSURE-RESPONSE RELATIONSHIPS IN TELAPREVIR COMBINATION THERAPY IN TREATMENT-NAIVE GENOTYPE 1 CHRONIC HCV PATIENTS
    Gordon, S. C.
    Muir, A. J.
    Garg, V.
    Henshaw, J.
    JOURNAL OF HEPATOLOGY, 2012, 56 : S440 - S440
  • [28] Exposure-Response Relationships in Telaprevir Combination Therapy in Treatment-NaiVE Genotype 1 Chronic HCV Patients
    Gordon, Stuart C.
    Muir, Andrew J.
    Garg, Varun
    Henshaw, Joshua W.
    GASTROENTEROLOGY, 2012, 142 (05) : S931 - S931
  • [29] Rapid Virological Response in PBMC with an Increase of HCV-Specific IFN-γ Production Predisposes to SVR in Patients with HCV Recurrence after Liver Transplantation with Genotype 1 Undergoing Peg-IFNa2a Plus Ribavirin
    Perrella, Alessandro
    Lanza, Alfonso
    Pisaniello, Donatella
    Di Costanzo, Giovanni
    Marcos, Amadeos
    Cuomo, Oreste
    LIVER TRANSPLANTATION, 2012, 18 : S246 - S246
  • [30] Persistent impairment of HCV-specific CD8 cell response in HCV-RNA negative patients after successful peg-interferon/ribavirin treatment
    Missale, G.
    Pilli, M.
    Penna, A.
    Zerbini, A.
    Sacchelli, L.
    Mori, C.
    Mezzadri, S.
    Ferrari, C.
    JOURNAL OF HEPATOLOGY, 2007, 46 : S42 - S42