Tracing Spatiotemporal T790M Heterogeneity in Patients with EGFR-Mutant Advanced NSCLC after Acquired Resistance to EGFR TKIs

被引：0
|
作者：
Zhang, Yi-Chen
Pi, Can
Ke, E-E
Chen, Zhi-Hong
Su, Jian
Dong, Zhong-Yi
Xu, Chong-Rui
Tu, Hai-Yan
Yan, Hong-Hong
Zhong, Wen-Zhao
Yang, Jin-Ji
Zhang, Xu-Chao
Wu, Yi Long
Zhou, Qing
机构：
[1] Guangdong Lung Canc Inst, Guangzhou, Guangdong, Peoples R China
[2] GGH, Guangzhou, Guangdong, Peoples R China
[3] Guangdong Acad Med Sci, Guangzhou, Guangdong, Peoples R China
来源：
JOURNAL OF THORACIC ONCOLOGY | 2017年 / 12卷 / 01期
关键词：
Acquired resistance; EGFR TKIs; spatiotemporal heterogeneity; T790M;
D O I：
10.1016/j.jtho.2016.11.1762
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
P3.02b-095
引用
收藏
页码：S1249 / S1249
页数：1
相关论文
共 50 条
  • [31] Baseline Spatial Heterogeneity of T790M in Tyrosine Kinase Inhibitor Naive EGFR-Mutant Lung Adenocarcinomas
    Cabanero, M.
    Kuo, J.
    Liu, N.
    Tsao, M.
    JOURNAL OF THORACIC ONCOLOGY, 2018, 13 (10) : S443 - S443
  • [32] Spatiotemporal T790M heterogeneity in individual patients with non-small cell lung cancer (NSCLC) after acquired resistance to EGFR-tyrosine kinase inhibitor (TKI)
    Hata, Akito
    Katakami, Nobuyuki
    Yoshioka, Hiroshige
    Masago, Katsuhiro
    Fujita, Shiro
    Imai, Yukihiro
    Tomii, Keisuke
    Nishiyama, Akihiro
    Ishida, Tadashi
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [33] NGS reveals potential druggable targets and molecular heterogeneity in EGFR mutant NSCLC with acquired resistance to EGFR TKIs
    Lee, Choong-Kun
    Kim, Sora
    Lee, Jae Seok
    Kim, Hye Ryun
    Kim, Joo-Hang
    Kim, Sang Woo
    Cho, Byoung Chul
    JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (09) : S586 - S586
  • [34] Efficacy of YK-029A, a novel EGFR TKI, in advanced NSCLC patients with acquired T790M mutation
    Wan, Rui
    Chau, Yi Fung
    Zhao, Jun
    Liu, Zhe
    Zhao, Mingfang
    Zhao, Yanqiu
    Dai, Xiumei
    Pan, Yueyin
    Zhang, Zhihong
    Yao, Yu
    Yang, Kunyu
    Wu, Lin
    Xie, Yanyan
    Chen, Bi
    Yang, Yixuan
    Guo, Yongqi
    Wang, Jie
    Duan, Jianchun
    CANCER RESEARCH, 2024, 84 (07)
  • [35] Mutational monitoring of EGFR T790M in cfDNA for clinical outcome prediction in EGFR-mutant lung adenocarcinoma
    Su, Kang-Yi
    Tseng, Jeng-Sen
    Liao, Keng-Mao
    Yang, Tsung-Ying
    Chen, Kun-Chieh
    Hsu, Kuo-Hsuan
    Yang, Pan-Chyr
    Yu, Sung-Liang
    Chang, Gee-Chen
    PLOS ONE, 2018, 13 (11):
  • [36] Tepotinib Plus an EGFR TKI in Patients with EGFR-mutant NSCLC and Resistance to EGFR TKIs Due to MET Amplification (METamp)
    Liam, C. K.
    Ahmad, A. Rozila
    Hsia, T.
    Li, J. Y.
    Le, X.
    Heymach, J.
    Yang, J. C.
    Soo, R.
    Zhang, Y.
    Kim, S.
    Shin, S. W.
    Johne, A.
    Karachaliou, N.
    Bruns, R.
    Ellers-Lenz, B.
    Wu, Y.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (10) : S1118 - S1119
  • [37] CNS Activity of Ramucirumab in Combination with Osimertinib in Patients with Advanced T790M-Positive EGFR-Mutant NSCLC
    Paz-Ares, L.
    Planchard, D.
    Yang, J. C.
    Lee, K.
    Garrido, P.
    Park, K. K.
    Kim, J.
    Lee, D. H.
    Mao, H.
    Chao, B.
    Yu, H.
    JOURNAL OF THORACIC ONCOLOGY, 2018, 13 (10) : S453 - S454
  • [38] Loss of T790M Mutation is Associated with Early Progression to Osimertinib in Chinese Advanced NSCLC Patients Harboring EGFR T790M
    Zhao, S.
    Jiang, T.
    Li, X.
    Zhao, C.
    Su, C.
    Ren, S.
    Zhou, C.
    JOURNAL OF THORACIC ONCOLOGY, 2018, 13 (10) : S410 - S410
  • [39] Sensitivity to chemotherapeutics of NSCLC cells with acquired resistance to EGFR-TKIs is mediated by T790M mutation or epithelial-mesenchymal transition
    Zhou, Juan
    Hu, Qiaoting
    Zhang, Xi
    Zheng, Jihua
    Xie, Bo
    Xu, Zhiyong
    Zhang, Weimin
    ONCOLOGY REPORTS, 2018, 39 (04) : 1783 - 1792
  • [40] Monitoring of T790M in plasma ctDNA of advanced EGFR-mutant NSCLC patients on first- or second-generation tyrosine kinase inhibitors
    Chun-Ta Huang
    Chih-An Lin
    Te-Jen Su
    Ching-Yao Yang
    Tzu-Hsiu Tsai
    Chia-Lin Hsu
    Wei-Yu Liao
    Kuan-Yu Chen
    Chao-Chi Ho
    Chong-Jen Yu
    BMC Cancer, 23
12345