New water-soluble phthalocyanines and other tetrapyrroles for application in photodynamic therapy

被引：0
|
作者：
Liu, W [1 ]
Kumar, MR [1 ]
Vicente, MGH [1 ]
Fronczek, FR [1 ]
Smith, KM [1 ]
机构：
[1] Louisiana State Univ, Dept Chem, Baton Rouge, LA 70803 USA
来源：
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIV | 2005年 / 5689卷
关键词：
aggregation; phthalocyanines; photodynamic therapy; synthesis; water-solubility; tetrabenzoporphyrins; tetrabutanoporphyrins;
D O I：
10.1117/12.588634
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The syntheses and properties of novel water-soluble phthalocyanies are reported, as well as new chemistry of tetrabutanoporphyrins aimed at the preparation of new, functionalizable, tribenzoporphyrin systems. The objective of the study is to provide new second-generation photosensitizing drugs, with long-wavelength absorption, for use in the photodynamic therapy of tumors.
引用
收藏
页码：39 / 47
页数：9
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