Membrane Trafficking: Licensing a Cargo Receptor for ER Export

被引:3
|
作者
Fromme, J. Christopher [1 ]
机构
[1] Cornell Univ, Dept Mol Biol & Genet, Weill Inst Cell & Mol Biol, Ithaca, NY 14853 USA
关键词
GPI-ANCHORED PROTEINS; COPII-COATED VESICLES; ENDOPLASMIC-RETICULUM; INOSITOL DEACYLATION; TRANSPORT VESICLES; GOLGI TRANSPORT; COMPONENT; COMPLEX; EMP24P; YEAST;
D O I
10.1016/j.cub.2014.11.051
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Quality control in the endoplasmic reticulum prevents packaging of immature and misfolded proteins into vesicles, but the actual mechanisms involved in this process have not been defined for most cargos. A recent study demonstrates that the engagement of mature cargo with its receptor triggers the recruitment of a vesicle cargo adaptor.
引用
收藏
页码:R67 / R68
页数:2
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