The efficient preparation of α-substituted serine scaffolds as the chiral building blocks for the synthesis of SPT inhibitors

被引：6

作者：

Martinkova, Miroslava ^{[1
]}

Gonda, Jozef ^{[1
]}

Raschmanova, Jana ^{[1
]}

Vojtickova, Margareta ^{[1
]}

机构：

[1] Safarik Univ, Inst Chem Sci, Dept Organ Chem, SK-04001 Kosice, Slovakia

来源：

TETRAHEDRON | 2007年 / 63卷 / 43期

关键词：

D O I：

10.1016/j.tet.2007.08.019

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient stereoselective synthesis of unusual substituted serine synthons 7, 10, 12 is reported. It was shown that highly functionalized furanose 6 has the suitable structure for further synthetic manipulations toward the inhibitors of SPT. (C) 2007 Published by Elsevier Ltd.

引用

页码：10603 / 10607

页数：5

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