CHARACTERIZATION OF PK/PD OF ANIFROLUMAB IN PATIENTS WITH MODERATE TO SEVERE SLE

被引：3
|
作者：
Chia, Y. L. [1 ]
Tummala, R. [2 ]
Mai, T. [3 ,4 ]
Rouse, T.
White, W. [2 ]
Morand, E. F. [5 ]
Furie, R. [6 ]
机构：
[1] AstraZeneca, BioPharmaceut R&D, San Francisco, CA USA
[2] AstraZeneca, BioPharmaceut R&D, Gaithersburg, MD USA
[3] Genentech Inc, Clin Pharmacol & Modeling & Simulat, San Francisco, CA USA
[4] AstraZeneca, BioPharmaceut R&D, Gothenburg, Sweden
[5] Monash Univ, Ctr Inflammatory Dis Monash Hlth, Melbourne, Vic, Australia
[6] Zucker Sch Med Hofstra Northwell, Div Rheumatol, Great Neck, NY USA
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2021年 / 80卷
关键词：
D O I：
10.1136/annrheumdis-2021-eular.1464
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
POS0688
引用
收藏
页码：590 / 591
页数：2
相关论文
共 50 条
  • [21] Pharmacokinetic/pharniacodynamic (PK/PD) modeling and simulation of CNTO 1275 in subjects with moderate to severe psoriasis vulgaris.
    Zhu, Yaowei
    Yeilding, Newman
    Guzzo, Cynthia
    Marini, Joseph
    Mascelli, Mary Ann
    Davis, Hugh
    Zhou, Honghui
    JOURNAL OF CLINICAL PHARMACOLOGY, 2007, 47 (09): : 1203 - 1203
  • [22] Fontolizumab (HuZAF™) pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity and exposure/response relationship in patients (Pts) with moderate and severe Crohn's disease (CD)
    Ding, H
    Maia, M
    Keller, S
    Colombel, JF
    van Deventer, S
    Gendre, JP
    Reinisch, W
    Rutgeerts, P
    Tang, MT
    GASTROENTEROLOGY, 2004, 126 (04) : A465 - A465
  • [23] EFFICACY AND SAFETY OF ANIFROLUMAB IN PATIENTS WITH MODERATE TO SEVERE SYSTEMIC LUPUS ERYTHEMATOSUS: RESULTS OF THE SECOND PHASE 3 RANDOMIZED CONTROLLED TRIAL
    Morand, Eric F.
    Furie, Richard
    Tanaka, Yoshiya
    Bruce, Ian N.
    Askanase, Anca D.
    Richez, Christophe
    Bae, Sang-Cheol
    Brohawn, Mr Philip Z.
    Pineda, Lilia
    Berglind, Anna
    Tummala, Raj
    INTERNAL MEDICINE JOURNAL, 2020, 50 : 22 - 23
  • [24] SLE Treatment History and Anifrolumab Efficacy by Baseline Standard Therapies in Patients with SLE from 2 Phase 3 Trials
    Manzi, Susan
    Furie, Richard
    Morand, Eric
    Tanaka, Yoshiya
    Abreu, Gabriel
    Lindholm, Catharina
    Tummala, Raj
    ARTHRITIS & RHEUMATOLOGY, 2021, 73 : 3623 - 3625
  • [25] Systemic Lupus Erythematosus (SLE) Responder Index [SRI(4)] Response Is Associated with Global Benefit in Patients with Moderate to Severe SLE
    Furie, R.
    Wang, L.
    Drappa, J.
    Illei, G.
    ARTHRITIS & RHEUMATOLOGY, 2016, 68
  • [26] SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) RESPONDER INDEX [SRI(4)] RESPONSE IS ASSOCIATED WITH GLOBAL BENEFIT IN PATIENTS WITH MODERATE TO SEVERE SLE
    Furie, R.
    Wang, L.
    Drappa, J.
    Illei, G.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2016, 34 (04) : S87 - S87
  • [27] Pharmacokinetics (PK), Effectiveness and Safety of Open-label (OL) Tofacitinib for the Treatment of Moderate to Severe Skin Involvement in Young Adults with SLE
    Romankevych, Ivanna
    Singer, Nora
    Marathe, Kaliyani
    Merritt, Angela
    Ogbu, Ekemini
    Chen, Chen
    Quinlan-Waters, Megan
    Pelletier, Kathleen
    Shi, Haihong
    Wang, Xiaoxing
    Huang, Bin
    Brunner, Hermine
    ARTHRITIS & RHEUMATOLOGY, 2024, 76 : 1390 - 1393
  • [28] ECONOMIC EVALUATIONS OF ANIFROLUMAB FOR THE MANAGEMENT OF PATIENTS AFFECTED BY SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) IN ITALY
    Fortunato, A.
    Di Brino, E.
    Rumi, F.
    Basile, M.
    Antonini, D.
    Falasca, G.
    Di Pippo, S.
    VALUE IN HEALTH, 2024, 27 (12)
  • [29] Efficacy of Anifrolumab in Serological Subgroups of Patients with SLE Participating in 2 Phase 3 Trials
    Bruce, Ian N.
    Van Vollenhoven, Ronald
    Tanaka, Yoshiya
    Morand, Eric
    Furie, Richard
    Psachoulia, Konstantina
    Maho, Emmanuelle
    Lindholm, Catharina
    Kleoudis, Christi
    Tummala, Raj
    ARTHRITIS & RHEUMATOLOGY, 2021, 73 : 3631 - 3633
  • [30] Efficacy and Safety of Anifrolumab in Patients with Moderate to Severe Systemic Lupus Erythematosus: Results of the Second Phase 3 Randomized Controlled Trial
    Morand, Eric
    Furie, Richard
    Tanaka, Yoshiya
    Bruce, Ian
    Askanase, Anca
    Riche'z, Christophe
    Bae, Sang-Cheol
    Brohawn, Philip
    Pineda, Lilia
    Berglind, Anna
    Tummala, Raj
    ARTHRITIS & RHEUMATOLOGY, 2019, 71
12345