COX-2 and PGE2 promote cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of EGFR and AKT

被引:0
|
作者
Han, C [1 ]
Demetris, AJ [1 ]
Wu, T [1 ]
机构
[1] Univ Pittsburgh, Dept Pathol, Pittsburgh, PA 15213 USA
来源
FASEB JOURNAL | 2005年 / 19卷 / 05期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:A1046 / A1046
页数:1
相关论文
共 50 条
  • [31] Role of PGE2 EP1 Receptor in Intracerebral Hemorrhage-Induced Brain Injury
    Singh, Nilendra
    Ma, Bo
    Leonardo, Christopher Charles
    Ahmad, Abdullah Shafique
    Narumiya, Shuh
    Dore, Sylvain
    NEUROTOXICITY RESEARCH, 2013, 24 (04) : 549 - 559
  • [32] COX-2 promotes intravitreal neovascularization via a PGE2/EP3 receptor-dependent mechanism
    Sennlaub, F
    Vazquez-Tello, A
    Checchin, D
    Brault, S
    Beauchamp, M
    Gobeil, F
    Chemtob, S
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2003, 44 : U77 - U77
  • [33] PGE2 maintains the tone of the guinea pig trachea through a balance between activation of contractile EP1 receptors and relaxant EP2 receptors
    Safholm, J.
    Dahlen, S-E
    Delin, I.
    Maxey, K.
    Stark, K.
    Cardell, L-O
    Adner, M.
    BRITISH JOURNAL OF PHARMACOLOGY, 2013, 168 (04) : 794 - 806
  • [34] PGE2 receptor EP1 renders dopaminergic neurons selectively vulnerable to low-level oxidative stress and direct PGE2 neurotoxicity
    Carrasco, Emilce
    Casper, Diana
    Werner, Peter
    JOURNAL OF NEUROSCIENCE RESEARCH, 2007, 85 (14) : 3109 - 3117
  • [35] Antagonism of the prostaglandin E2 EP1 receptor in MDCK cells increases growth through activation of Akt and the epidermal growth factor receptor
    Taub, Mary
    Mathivanan, Paremala
    Parker, Robert
    Rudra, Trina
    Ariff, Mohamad
    FASEB JOURNAL, 2014, 28 (01):
  • [36] EFFECTS OF B CELL COX-2/PGE2 ON ACTIVATION-INDUCED CYTOSINE DEAMINASE (AID)
    Mongini, Patricia K. A.
    JOURNAL OF IMMUNOLOGY, 2007, 178
  • [37] Antagonism of the prostaglandin E2 EP1 receptor in MDCK cells increases growth through activation of Akt and the epidermal growth factor receptor
    Taub, Mary
    Parker, Robert
    Mathivanan, Paremala
    Ariff, Muhamad Asnawi Mohd
    Rudra, Trina
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2014, 307 (05) : F539 - F550
  • [38] Micturition patterns in response to PGE2 and bladder outlet obstruction in EP1 receptor knockout mice
    Schröder, A
    Newgreen, D
    Andersson, KE
    JOURNAL OF UROLOGY, 2004, 171 (04): : 453 - 453
  • [39] PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-β signaling during mammary tumorigenesis
    Tian, Maozhen
    Schiemann, William P.
    FASEB JOURNAL, 2010, 24 (04): : 1105 - 1116
  • [40] PGE2 upregulated COX-2 expressed in VEGF treated endothelial cells via EP2 receptor and MEK kinase
    Akarasereenont, Pravit
    Techatraisak, Kitirat
    Thaworn, Athiwat
    Chotewuttakorn, Sirikul
    INFLAMMATION RESEARCH, 2005, 54 : S159 - S159