GC-MS Determination of Trace Amounts of Pharmaceuticals in Drinking Water

被引：0
|
作者：
Pomykacova, Ivana [1 ]
Cadek, Vaclav [1 ]
Svobodova, Veronika [1 ]
Kozisek, Frantisek [1 ]
Jeligova, Hana [1 ]
机构：
[1] Natl Inst Publ Hlth, Dept Water Hyg, Prague, Czech Republic
来源：
CHEMICKE LISTY | 2012年 / 106卷 / 02期
关键词：
NONSTEROIDAL ANTIINFLAMMATORY DRUGS; GAS-CHROMATOGRAPHY;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The aim of this study was GC-MS screening of drinking water supplies for the presence of traces of pharmaceuticals. The target analytes were naproxen, ibuprofen, diclofenac, carbamazepine and 17 alpha-ethynylestradiol. Solid -phase extraction (SPE) was used for for their preconcetration. Derivatization of target analytes in the eluted extracts was performed using N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide. Limits of quantification were less than 0.5 ng/L for naproxen, ibuprofen, diclofenac, carbamazepine and less than 2.0 ng/L for 17 alpha-ethynylestradiol. The presence of target pharmaceuticals in drinking water in the Czech Republic is very rare; their concentrations range on the ng/L level.
引用
收藏
页码：143 / 148
页数：6
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