GC-MS Determination of Trace Amounts of Pharmaceuticals in Drinking Water

被引：0

作者：

Pomykacova, Ivana ^{[1
]}

Cadek, Vaclav ^{[1
]}

Svobodova, Veronika ^{[1
]}

Kozisek, Frantisek ^{[1
]}

Jeligova, Hana ^{[1
]}

机构：

[1] Natl Inst Publ Hlth, Dept Water Hyg, Prague, Czech Republic

来源：

CHEMICKE LISTY | 2012年 / 106卷 / 02期

关键词：

NONSTEROIDAL ANTIINFLAMMATORY DRUGS; GAS-CHROMATOGRAPHY;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The aim of this study was GC-MS screening of drinking water supplies for the presence of traces of pharmaceuticals. The target analytes were naproxen, ibuprofen, diclofenac, carbamazepine and 17 alpha-ethynylestradiol. Solid -phase extraction (SPE) was used for for their preconcetration. Derivatization of target analytes in the eluted extracts was performed using N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide. Limits of quantification were less than 0.5 ng/L for naproxen, ibuprofen, diclofenac, carbamazepine and less than 2.0 ng/L for 17 alpha-ethynylestradiol. The presence of target pharmaceuticals in drinking water in the Czech Republic is very rare; their concentrations range on the ng/L level.

引用

页码：143 / 148

页数：6

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