Metabolic alterations due to IDH1 mutation in glioma: opening for therapeutic opportunities?

被引:23
|
作者
Mustafa, Dana A. N. [1 ]
Swagemakers, Sigrid M. [2 ]
Buise, Laura [1 ]
van der Spek, Peter J. [2 ]
Kros, Johan M. [1 ]
机构
[1] Erasmus MC, Dept Pathol, Dr Molewaterplein 50, NL-3000 CA Rotterdam, Netherlands
[2] Erasmus MC, Dept Bio Informat, NL-3015 GE Rotterdam, Netherlands
来源
关键词
Astrocytoma; Pyruvate Kinase; Oligodendroglioma; IDH1 Mutation; Aerobic Glycolysis;
D O I
10.1186/2051-5960-2-6
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页数:3
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