IL-1β-induced expression of IL-6 is a critical event in regulating the expression of collagenase-3 (MMP-13) in human OA chondrocytes

被引:0
|
作者
Haqqi, TM [1 ]
Ahmed, S [1 ]
Lalonde, M [1 ]
Whang, N [1 ]
Khan, SA [1 ]
Goldberg, VM [1 ]
机构
[1] Case Western Reserve Univ, Cleveland, OH 44106 USA
来源
ARTHRITIS AND RHEUMATISM | 2003年 / 48卷 / 09期
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
56
引用
收藏
页码:S68 / S68
页数:1
相关论文
共 50 条
  • [21] Increased expression of collagenase-3 (MMP-13) and MT1-MMP in oesophageal cancer is related to cancer aggressiveness
    Etoh, T
    Inoue, H
    Yoshikawa, Y
    Barnard, GF
    Kitano, S
    Mori, M
    GUT, 2000, 47 (01) : 50 - 56
  • [22] HDAC INHIBITOR SAHA INDUCES MCPIP1 EXPRESSION AND SUPPRESSES IL-6 EXPRESSION IN HUMAN OA CHONDROCYTES
    Makki, M. S.
    Haqqi, T. M.
    OSTEOARTHRITIS AND CARTILAGE, 2015, 23 : A156 - A156
  • [23] Mechanism of TNFα-induced IL-1α, IL-1β and IL-6 expression in human cardiac fibroblasts:: Effects of statins and thiazolidinediones
    Turner, Neil A.
    Mughal, Romana S.
    Warburton, Philip
    O'Regan, David J.
    Ball, Stephen G.
    Porter, Karen E.
    CARDIOVASCULAR RESEARCH, 2007, 76 (01) : 81 - 90
  • [24] IL-1β INDUCES LOW LEVELS OF AUTOPHAGY WHICH CLEARS DYSFUNCTIONAL MITOCHONDRIA AND INHIBITS ROS, MMP-13 AND ADAMTS5 EXPRESSION IN OA CHONDROCYTES
    Ansari, M. Y.
    Khan, M. N.
    Haqqi, T. M.
    OSTEOARTHRITIS AND CARTILAGE, 2016, 24 : S135 - S136
  • [25] Expression of collagenase-3 (MMP-13) in human abdominal aortic aneurysms and vascular smooth muscle cells in culture
    Mao, DL
    Lee, JK
    Van Vickle, SJ
    Thompson, RW
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1999, 261 (03) : 904 - 910
  • [26] Targeted inhibition of human collagenase-3 (MMP-13) expression inhibits squamous cell carcinoma growth in vivo
    Risto Ala-aho
    Matti Ahonen
    Sarah J George
    Jari Heikkilä
    Reidar Grénman
    Markku Kallajoki
    Veli-Matti Kähäri
    Oncogene, 2004, 23 : 5111 - 5123
  • [27] Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice
    Neuhold, LA
    Killar, L
    Zhao, WG
    Sung, MLA
    Warner, L
    Kulik, J
    Turner, J
    Wu, W
    Billinghurst, C
    Meijers, T
    Poole, AR
    Babij, P
    DeGennaro, LJ
    JOURNAL OF CLINICAL INVESTIGATION, 2001, 107 (01): : 35 - 44
  • [28] Targeted inhibition of human collagenase-3 (MMP-13) expression inhibits squamous cell carcinoma growth in vivo
    Ala-aho, R
    Ahonen, M
    George, SJ
    Heikkilä, J
    Grènman, R
    Kallajoki, M
    Kähäri, VM
    ONCOGENE, 2004, 23 (30) : 5111 - 5123
  • [29] SERPINE2 Inhibits IL-1α-Induced MMP-13 Expression in Human Chondrocytes: Involvement of ERK/NF-κB/AP-1 Pathways
    Santoro, Anna
    Conde, Javier
    Scotece, Morena
    Abella, Vanessa
    Lois, Ana
    Lopez, Veronica
    Pino, Jesus
    Gomez, Rodolfo
    Gomez-Reino, Juan J.
    Gualillo, Oreste
    PLOS ONE, 2015, 10 (08):
  • [30] Expression of collagenase-3 (MMP-13) by tumor cells in squamous cell carcinomas of the head and neck
    Kähäri, VM
    Johansson, N
    Grénman, R
    Airola, K
    Saarialho-Kere, U
    GENE THERAPY OF CANCER, 1998, 451 : 63 - 68