A DNA Damage Repair Signature in Pediatric High-Grade Gliomas: XRCC1 and PARP1, Key Biomarkers

被引:0
|
作者
Entz-Werle, N. [1 ]
Poidevin, L. [2 ]
Nazarov, P. [3 ]
Lhermitte, B. [4 ]
Poch, O. [2 ]
Dontenwill, M. [5 ]
Van Dyck, E. [6 ]
机构
[1] Univ Strasbourg, Dept Pediat Hematol & Oncol, UMR 7021, CNRS, Strasbourg, France
[2] Univ Strasbourg, Icube, France
[3] Luxembourg Inst Hlth, Multiom Data Sci, Dept Oncol & Bioinformat Platform, Luxembourg, Luxembourg
[4] Univ Hosp Strasbourg, Pathol Dept, Strasbourg, France
[5] Lab Biopathol & Imaging, CNRS, UMR 7021, Tumoral Signalling Team, Reims, France
[6] Luxembourg Inst Hlth, Dna Repair & Chemoresistance, Dept Oncol, Luxembourg, Luxembourg
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
O0121
引用
收藏
页码:S59 / S59
页数:1
相关论文
共 50 条
  • [21] PARP1 regulates DNA damage-induced nucleolar-nucleoplasmic shuttling of WRN and XRCC1 in a toxicant and protein-specific manner
    Sebastian Veith
    Andrea Schink
    Marina Engbrecht
    Matthias Mack
    Lisa Rank
    Pascal Rossatti
    Mariam Hakobyan
    Denise Goly
    Tanja Hefele
    Marco Frensch
    Arthur Fischbach
    Alexander Bürkle
    Aswin Mangerich
    Scientific Reports, 9
  • [22] PARP1 blockade is synthetically lethal in XRCC1 deficient sporadic epithelial ovarian cancers
    Ali, Reem
    Alabdullah, Muslim
    Alblihy, Adel
    Miligy, Islam
    Mesquita, Katia A.
    Chan, Stephen YT.
    Moseley, Paul
    Rakha, Emad A.
    Madhusudan, Srinivasan
    CANCER LETTERS, 2020, 469 : 124 - 133
  • [23] PARP1 regulates DNA damage-induced nucleolar-nucleoplasmic shuttling of WRN and XRCC1 in a toxicant and protein-specific manner
    Veith, Sebastian
    Schink, Andrea
    Engbrecht, Marina
    Mack, Matthias
    Rank, Lisa
    Rossatti, Pascal
    Hakobyan, Mariam
    Goly, Denise
    Hefele, Tanja
    Frensch, Marco
    Fischbach, Arthur
    Buerkle, Alexander
    Mangerich, Aswin
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [24] DNA damage levels and biochemical repair capacities associated with XRCC1 deficiency
    Wong, HK
    Kim, DY
    Hogue, BA
    McNeill, DR
    Wilson, DM
    BIOCHEMISTRY, 2005, 44 (43) : 14335 - 14343
  • [25] Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses
    Horton, Julie K.
    Stefanick, Donna F.
    Gassman, Natalie R.
    Williams, Jason G.
    Gabel, Scott A.
    Cuneo, Matthew J.
    Prasad, Rajendra
    Kedar, Padmini S.
    DeRose, Eugene F.
    Hou, Esther W.
    London, Robert E.
    Wilson, Samuel H.
    DNA REPAIR, 2013, 12 (09) : 774 - 785
  • [26] A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage
    El-Khamisy, SF
    Masutani, M
    Suzuki, H
    Caldecott, KW
    NUCLEIC ACIDS RESEARCH, 2003, 31 (19) : 5526 - 5533
  • [27] Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells
    Duell, EJ
    Wiencke, JK
    Cheng, TJ
    Varkonyi, A
    Zuo, ZF
    Ashok, TDS
    Mark, EJ
    Wain, JC
    Christiani, DC
    Kelsey, KT
    CARCINOGENESIS, 2000, 21 (05) : 965 - 971
  • [28] FUCOIDAN FROM Fucus vesiculosus, REGULATES OXIDATIVE AND TRANSCRIPTIONAL RESPONSES IN THE SULFOXAFLOR EXPOSED MICE LIVER: ASSESMENT OF DNA DAMAGE GENES, THAT REPAIR DNA DAMAGE (XRCC1, OGG1, APE1, AND PARP1), AND THE ANTIOXIDANT STATUS
    Benli, P. Piner
    Daglioglu, Y. K.
    Coskun, C.
    JOURNAL OF ANIMAL AND PLANT SCIENCES-JAPS, 2025, 35 (01): : 90 - 105
  • [29] Exploring the Control of PARP1 Levels in High-Grade Serous Ovarian Cancer
    Raspaglio, Giuseppina
    Buttarelli, Marianna
    Cappoli, Natalia
    Ciucci, Alessandra
    Fagotti, Anna
    Scambia, Giovanni
    Gallo, Daniela
    CANCERS, 2023, 15 (08)
  • [30] Genetic polymorphisms in XRCC1, OGG1, and XRCC3 DNA repair genes and DNA damage in radiotherapy workers
    Soliman, Asmaa H. M.
    Zaki, Nasef N.
    Fathy, Hala M.
    Mohamed, Aml A.
    Ezzat, Mohamed A.
    Rayan, Amal
    ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2020, 27 (35) : 43786 - 43799