Bone marrow transplantation as treatment for X-linked immunodeficiency with hyper-IgM

被引：19
|
作者：
Bordigoni, P
Auburtin, B
Carret, AS
Schuhmacher, A
Humbert, JC
Le Deist, F
Sommelet, D
机构：
[1] Childrens Hosp, Bone Marrow Transplantat Unit, Nancy, France
[2] Hop Necker Enfants Malad, INSERM, U429, Paris, France
来源：
BONE MARROW TRANSPLANTATION | 1998年 / 22卷 / 11期
关键词：
X-linked immunodeficiency with hyper-IgM; bone marrow transplantation; CD40; ligand;
D O I：
10.1038/sj.bmt.1701497
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
We report a 10-year-old boy with a severe form of immunodeficiency with hyper-IgM who underwent successful bone marrow transplantation with his HLA-matched sister as donor. Busulfan (20 mg/kg) and cyclophosphamide (200 mg/kg) were used as conditioning. The post-transplant course was uneventful. He is alive 25 months later with full hematological and immunological reconstitution.
引用
收藏
页码：1111 / 1114
页数：4
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