THE CLASS II PHOSPHOINOSITIDE 3-KINASE ISOFORM β REGULATES PLATELET FUNCTION AND ARTERIAL THROMBOSIS IN MICE

被引:0
|
作者
Tibolla, G. [1 ,2 ]
Barbieri, S. S. [1 ]
Gianellini, S. [1 ]
Arnaboldi, L. [1 ]
Corsini, A. [1 ]
Tremoli, E. [1 ,3 ]
Falasca, M. [4 ]
Norata, G. D. [1 ,2 ]
Catapano, A. L. [1 ,2 ]
机构
[1] Univ Milan, Dept Pharmacol Sci, Milan, Italy
[2] Bassini Hosp, SISA Ctr Study Atherosclerosis, Cinisello Balsamo, Italy
[3] IRCCS Ctr Cardiol Monzino, Milan, Italy
[4] Queen Mary Univ London, Barts & London Sch Med & Dent, London, England
关键词
D O I
10.1016/S1567-5688(11)70456-1
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
455
引用
收藏
页码:97 / 97
页数:1
相关论文
共 50 条
  • [31] Towards an understanding of isoform specificity in phosphoinositide 3-kinase signalling in lymphocytes
    Fruman, DA
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2004, 32 : 315 - 319
  • [32] Discovery of Highly Isoform Selective Thiazolopiperidine Inhibitors of Phosphoinositide 3-Kinase γ
    Collier, Philip N.
    Messersmith, David
    Le Tiran, Arnaud
    Bandarage, Upul K.
    Boucher, Christina
    Come, Jon
    Cottrell, Kevin M.
    Damagnez, Veronique
    Doran, John D.
    Griffith, James P.
    Khare-Pandit, Suvama
    Krueger, Elaine B.
    Ledeboer, Mark W.
    Ledford, Brian
    Liao, Yusheng
    Mahajan, Sudipta
    Moody, Cameron S.
    Roday, Setu
    Wang, Tiansheng
    Xu, Jinwang
    Aronov, Alex M.
    JOURNAL OF MEDICINAL CHEMISTRY, 2015, 58 (14) : 5684 - 5688
  • [33] Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration
    Maffucci, T
    Cooke, FT
    Foster, FM
    Traer, CJ
    Fry, MJ
    Falasca, M
    JOURNAL OF CELL BIOLOGY, 2005, 169 (05): : 789 - 799
  • [34] Phosphoinositide 3-kinase class II beta is a novel target in breast cancer therapy
    Abbott, J.
    Pineiro, R.
    Oliviero, M. A.
    Lattanzio, R.
    Piantelli, M.
    Bilancio, A.
    Maffucci, T.
    Falasca, M.
    BREAST CANCER RESEARCH, 2010, 12 : S5 - S5
  • [35] Phosphoinositide 3-kinase class II beta is a novel target in breast cancer therapy
    J Abbott
    R Pineiro
    MA Oliviero
    R Lattanzio
    M Piantelli
    A Bilancio
    T Maffucci
    M Falasca
    Breast Cancer Research, 12
  • [36] Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression
    Chandrasekaran, Sanjay
    Sasaki, Maiko
    Scharer, Christopher D.
    Kissick, Haydn T.
    Patterson, Dillon G.
    Magliocca, Kelly R.
    Seykora, John T.
    Sapkota, Bishu
    Gutman, David A.
    Cooper, Lee A.
    Lesinski, Gregory B.
    Waller, Edmund K.
    Thomas, Susan N.
    Kotenko, Sergei V.
    Boss, Jeremy M.
    Moreno, Carlos S.
    Swerlick, Robert A.
    Pollack, Brian P.
    MOLECULAR CANCER RESEARCH, 2019, 17 (12) : 2395 - 2409
  • [37] The class II phosphoinositide 3-kinase C2β is not essential for epidermal differentiation
    Harada, K
    Truong, AB
    Cai, T
    Khavari, PA
    MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (24) : 11122 - 11130
  • [38] The role of class I phosphoinositide 3-kinase in T-cell function and autoimmunity
    Fruman, D. A.
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2007, 35 : 177 - 180
  • [39] Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes
    Mousavi, SA
    Brech, A
    Berg, T
    Kjeken, R
    BIOCHEMICAL JOURNAL, 2003, 372 : 861 - 869
  • [40] The class II phosphoinositide 3-kinase C2α is activated by clathrin and regulates clathrin-mediated membrane trafficking
    Gaidarov, I
    Smith, MEK
    Domin, J
    Keen, JH
    MOLECULAR CELL, 2001, 7 (02) : 443 - 449