Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery

被引：19

作者：

Cornman-Homonoff, Joshua ^{[1
,2
]}

Kuehn, Devon ^{[1
,3
]}

Aros, Sofia ^{[4
]}

Carter, Tonia C. ^{[1
]}

Conley, Mary R. ^{[1
]}

Troendle, James ^{[5
]}

Cassorla, Fernando ^{[6
]}

Mills, James L. ^{[1
]}

机构：

[1] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Div Epidemiol Stat & Prevent Res, NIH, Dept Hlth & Human Serv, Bethesda, MD USA

[2] Univ Penn, Sch Med, Philadelphia, PA 19104 USA

[3] Uniformed Serv Univ Hlth Sci, Dept Pediat, Bethesda, MD 20814 USA

[4] Univ Chile, Fac Med, Dept Pediat, San Borja Arriaran Clin Hosp, Santiago 7, Chile

[5] NHLBI, Div Cardiovasc Sci, NIH, Dept Hlth & Human Serv, Bethesda, MD 20892 USA

[6] Univ Chile, Fac Med, Inst Maternal & Child Res IDIMI, Santiago 7, Chile

来源：

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2012年 / 25卷 / 06期

关键词：

alcohol; pregnancy; stillbirth; preterm delivery; binge drinking; PREGNANCY; DEATH; CONSUMPTION; MORTALITY; DRINKING; BIRTH; CHILE;

D O I：

10.3109/14767058.2011.587559

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

We prospectively identified 96 women consuming at least 4 drinks/day during pregnancy by screening 9628 pregnant women. In these women with heavy prenatal alcohol use, there were three stillbirths and one preterm delivery; 98 matched nondrinking women had no stillbirths and two preterm births. Preterm rates did not differ significantly. The stillbirth rate was higher in the exposed group (p = 0.06). Additional investigation showed the stillbirth rate in the exposed population (3.1%) was significantly higher (p = 0.019) than the reported Chilean population rate (0.45%). Our data suggest that heavy alcohol consumption may increase the risk for stillbirth but not preterm delivery.

引用

页码：860 / 863

页数：4

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