Efficacy and Safety of Upadacitinib in Patients with Active Ankylosing Spondylitis: 2-Year Results from a Randomized, Double-Blind, Placebo-Controlled Study with Open-Label Extension

被引:0
|
作者
van der Heijde, Desiree [1 ]
Deodhar, Atul [2 ]
Maksymowych, Walter [3 ]
Sieper, Joachim [4 ,5 ,6 ]
Van den Bosch, Filip [7 ]
Kim, Tae-Hwan [8 ]
Kishimoto, Mitsumasa [9 ]
Ostor, Andrew [10 ,11 ]
Combe, Bernard [12 ]
Sui, Yunxia [13 ]
Duan, Yuanyuan [14 ]
Chu, Alvina D. [14 ]
Song, In-Ho [14 ]
机构
[1] Leiden Univ, Med Ctr, Dept Rheumatol, Meerssen, Netherlands
[2] Oregon Hlth & Sci Univ, Portland, OR 97201 USA
[3] Univ Alberta, Dept Med, Edmonton, AB, Canada
[4] Charite Univ Med Berlin, Dept Gastroenterol Infectiol & Rheumatol Includin, Berlin, Germany
[5] Free Univ Berlin, Berlin, Germany
[6] Humboldt Univ, Berlin, Germany
[7] Ghent Univ Hosp, Dept Rheumatol, Ghent, Belgium
[8] Hanyang Univ Hosp Rheumat Dis, Seoul, South Korea
[9] Kyorin Univ, Sch Med, Dept Nephrol & Rheumatol, Tokyo, Japan
[10] Monash Univ, Cabrini Hosp, Malvern, Australia
[11] Emertius Res, Malvern, Australia
[12] Montpellier Univ, Montpellier, France
[13] AbbVie, N Chicago, IL 60064 USA
[14] AbbVie Inc, N Chicago, IL USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
0924
引用
收藏
页码:1925 / 1928
页数:4
相关论文
共 50 条
  • [41] Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis (SELECT-AXIS 1): a multicentre, randomised, double-blind, placebo-controlled, phase 2/3 trial
    van der Heijde, Desiree
    Song, In-Ho
    Pangan, Aileen L.
    Deodhar, Atul
    van den Bosch, Filip
    Maksymowych, Walter P.
    Kim, Tae-Hwan
    Kishimoto, Mitsumasa
    Everding, Andrea
    Sui, Yunxia
    Wang, Xin
    Chu, Alvina D.
    Sieper, Joachim
    LANCET, 2019, 394 (10214): : 2108 - 2117
  • [42] Apararenone in patients with diabetic nephropathy: results of a randomized, double-blind, placebo-controlled phase 2 dose-response study and open-label extension study
    Wada, Takashi
    Inagaki, Masaya
    Yoshinari, Toru
    Terata, Ryuji
    Totsuka, Naoko
    Gotou, Miki
    Hashimoto, Gaia
    CLINICAL AND EXPERIMENTAL NEPHROLOGY, 2021, 25 (02) : 120 - 130
  • [43] A Phase II Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Lenalidomide in Lumbar Radicular Pain with a Long-Term Open-Label Extension Phase A Phase II Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Lenalidomide in Lumbar Radicular Pain with a Long-Term Open-Label Extension Phase
    Manning, Donald C.
    Gimbel, Joseph
    Wertz, Robert
    Rauck, Richard
    Cooper, Alyse
    Zeldis, Jerome B.
    Levinsky, Dale M.
    PAIN MEDICINE, 2017, 18 (03) : 477 - 487
  • [44] A 2-year comparative open label randomized study of efficacy and safety of etanercept and infliximab in patients with ankylosing spondylitis
    Anna Rita Giardina
    Angelo Ferrante
    Francesco Ciccia
    Rosalia Impastato
    Maria Concetta Miceli
    Alfonso Principato
    Giovanni Triolo
    Rheumatology International, 2010, 30 : 1437 - 1440
  • [45] A 2-year comparative open label randomized study of efficacy and safety of etanercept and infliximab in patients with ankylosing spondylitis
    Giardina, Anna Rita
    Ferrante, Angelo
    Ciccia, Francesco
    Impastato, Rosalia
    Miceli, Maria Concetta
    Principato, Alfonso
    Triolo, Giovanni
    RHEUMATOLOGY INTERNATIONAL, 2010, 30 (11) : 1437 - 1440
  • [46] Efficacy of etanercept (Enbrel®) in the treatment of ankylosing spondylitis:: A randomized, placebo-controlled, double-blind study.
    Gorman, JD
    Sack, KE
    Davis, JC
    ARTHRITIS AND RHEUMATISM, 2001, 44 (12): : 2947 - 2947
  • [47] A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study with an Open-label Extension Period to Evaluate the Efficacy and Safety of Telitacicept in Patients with Generalized Myasthenia Gravis (RG)
    Zuraw, Qing
    Cui, Xiaoming
    Fang, Jianmin
    ANNALS OF NEUROLOGY, 2024, 96 : S86 - S87
  • [48] Safety and efficacy of combination therapy of iguratimod with methotrexate for patients with active rheumatoid arthritis with an inadequate response to methotrexate: An open-label extension of a randomized, double-blind, placebo-controlled trial
    Hara, Masako
    Ishiguro, Naoki
    Katayama, Kou
    Kondo, Masakazu
    Sumida, Takayuki
    Mimori, Tsuneyo
    Soen, Satoshi
    Nagai, Kota
    Yamaguchi, Tomonobu
    Yamamoto, Kazuhiko
    MODERN RHEUMATOLOGY, 2014, 24 (03) : 410 - 418
  • [49] Belumosudil in diffuse cutaneous systemic sclerosis: a randomized, double-blind, open-label extension, placebo-controlled, phase 2 study
    Chung, Lorinda
    Silver, Richard M.
    Steen, Virginia
    Furst, Daniel E.
    Castelino, Flavia, V
    Trojanowski, Marcin
    Spiera, Robert
    Domsic, Robyn
    Rodriguez-Pla, Alicia
    Katsumoto, Tamiko R.
    Goulaouic, Helene
    Wang, Hong
    Espinasse, Melanie
    El-Chemaly, Souheil
    Wang, Rui
    RHEUMATOLOGY, 2025,
  • [50] Safety and Efficacy of Memantine in Children with Autism: Randomized, Placebo-Controlled Study and Open-Label Extension
    Aman, Michael G.
    Findling, Robert L.
    Hardan, Antonio Y.
    Hendren, Robert L.
    Melmed, Raun D.
    Kehinde-Nelson, Ola
    Hsu, Hai-An
    Trugman, Joel M.
    Palmer, Robert H.
    Graham, Stephen M.
    Gage, Allyson T.
    Perhach, James L.
    Katz, Ephraim
    JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 2017, 27 (05) : 403 - 412