Elements of Th1/Th2 response and disease severity in COVID-19 patients: A short report

被引：2

作者：

Akinosoglou, Karolina ^{[1
,2
]}

Delastic, Anne-Lise ^{[1
]}

Dimakopoulou, Vasilina ^{[1
]}

Marangos, Markos ^{[1
,2
]}

Gogos, Charalambos ^{[1
,2
]}

机构：

[1] Univ Patras, Dept Internal Med, Rion, Greece

[2] Univ Patras, Dept Infect Dis, Rion, Greece

来源：

JOURNAL OF MEDICAL VIROLOGY | 2022年 / 94卷 / 01期

关键词：

COVID-19; inflammation; SARS-CoV-2; Th1; Th2; response;

D O I：

10.1002/jmv.27313

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The presence of a complex immune dysregulation syndrome has been established in COVID-19 patients. We aimed to assess Th1/Th2 response in COVID-19 patients and its association with disease severity by performing a prospective cohort study in a tertiary hospital COVID-19 referral center. We report no difference between Th1/Th2 responses between patients with severe and mild disease, except for levels of interleukin-6 (IL-6) and IL-10. Future larger studies should examine lung-specific versus systemic inflammatory responses, as well as, diverse immunotypes driving poor clinical outcomes.

引用

页码：404 / 406

页数：3

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