Elements of Th1/Th2 response and disease severity in COVID-19 patients: A short report

被引：2
|
作者：
Akinosoglou, Karolina [1 ,2 ]
Delastic, Anne-Lise [1 ]
Dimakopoulou, Vasilina [1 ]
Marangos, Markos [1 ,2 ]
Gogos, Charalambos [1 ,2 ]
机构：
[1] Univ Patras, Dept Internal Med, Rion, Greece
[2] Univ Patras, Dept Infect Dis, Rion, Greece
来源：
JOURNAL OF MEDICAL VIROLOGY | 2022年 / 94卷 / 01期
关键词：
COVID-19; inflammation; SARS-CoV-2; Th1; Th2; response;
D O I：
10.1002/jmv.27313
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The presence of a complex immune dysregulation syndrome has been established in COVID-19 patients. We aimed to assess Th1/Th2 response in COVID-19 patients and its association with disease severity by performing a prospective cohort study in a tertiary hospital COVID-19 referral center. We report no difference between Th1/Th2 responses between patients with severe and mild disease, except for levels of interleukin-6 (IL-6) and IL-10. Future larger studies should examine lung-specific versus systemic inflammatory responses, as well as, diverse immunotypes driving poor clinical outcomes.
引用
收藏
页码：404 / 406
页数：3
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