Zebrafish as a New Model to Study the Crosstalk between Tumor and Host Metabolism

被引：5

作者：

Montal, Emily ^{[1
]}

White, Richard M. ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Canc Biol & Genet, 1275 York Ave, New York, NY 10021 USA

来源：

TRENDS IN CANCER | 2021年 / 7卷 / 08期

关键词：

D O I：

10.1016/j.trecan.2021.06.006

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The mechanism of metabolic crosstalk between different tissues in the host remains poorly understood but is likely to play important roles in tumor growth and cachexia. A recent study from Naser, Jackstadt, et al. utilizes isotope tracing in a zebrafish melanoma model and finds that tumors secrete alanine into circulation, which is taken up by the liver and used for gluconeogenesis.

引用

页码：661 / 663

页数：3

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