Zebrafish as a New Model to Study the Crosstalk between Tumor and Host Metabolism

被引：5
|
作者：
Montal, Emily [1 ]
White, Richard M. [1 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Canc Biol & Genet, 1275 York Ave, New York, NY 10021 USA
来源：
TRENDS IN CANCER | 2021年 / 7卷 / 08期
关键词：
D O I：
10.1016/j.trecan.2021.06.006
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The mechanism of metabolic crosstalk between different tissues in the host remains poorly understood but is likely to play important roles in tumor growth and cachexia. A recent study from Naser, Jackstadt, et al. utilizes isotope tracing in a zebrafish melanoma model and finds that tumors secrete alanine into circulation, which is taken up by the liver and used for gluconeogenesis.
引用
收藏
页码：661 / 663
页数：3
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