Meningococcal serogroup B vaccines

被引:0
|
作者
Dommergues, M. -A. [1 ]
机构
[1] Ctr Hosp Versailles, F-78150 Le Chesnay, France
来源
ARCHIVES DE PEDIATRIE | 2012年 / 19卷
关键词
RECOMBINANT PROTEIN; TAILOR-MADE; COVERAGE; SAFETY;
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The diversity and antigenic variability of Neisseria meningitidis serogroup B strains around the world has been a major challenge to developing a vaccine with broad coverage. Outer-membrane vesicle vaccines appear to be safe and effective but are strain-specific vaccines and used in delimited areas. Also, recombinant protein vaccines such as factor H binding protein, given alone or in combination with others antigens have been developed and may be effective against the majority of group B strains. (c) 2012 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:S65 / S69
页数:5
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