Meningococcal serogroup B vaccines

被引：0
|
作者：
Dommergues, M. -A. [1 ]
机构：
[1] Ctr Hosp Versailles, F-78150 Le Chesnay, France
来源：
ARCHIVES DE PEDIATRIE | 2012年 / 19卷
关键词：
RECOMBINANT PROTEIN; TAILOR-MADE; COVERAGE; SAFETY;
D O I：
暂无
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The diversity and antigenic variability of Neisseria meningitidis serogroup B strains around the world has been a major challenge to developing a vaccine with broad coverage. Outer-membrane vesicle vaccines appear to be safe and effective but are strain-specific vaccines and used in delimited areas. Also, recombinant protein vaccines such as factor H binding protein, given alone or in combination with others antigens have been developed and may be effective against the majority of group B strains. (c) 2012 Elsevier Masson SAS. All rights reserved.
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页码：S65 / S69
页数：5
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