A polymeric molecular "Handle" for multiple AFM-based single-molecule force measurements

被引：31
|
作者：
Valle, Francesco [1 ,2 ]
Zuccheri, Giampaolo [1 ,2 ,5 ]
Bergia, Anna [1 ]
Ayres, Lee [6 ]
Rowan, Alan E. [4 ]
Nolte, Roeland J. M. [4 ]
Samori, Bruno [1 ,2 ,3 ]
机构：
[1] Univ Bologna, Dept Biochem, I-40126 Bologna, Italy
[2] Univ Bologna, Natl Inst Phys Matter S3, I-40126 Bologna, Italy
[3] Univ Bologna, Interdepartmental Ctr L Galvani, I-40126 Bologna, Italy
[4] Radboud Univ Nijmegen, Inst Mol & Mat, NL-6525 ED Nijmegen, Netherlands
[5] Univ Bologna, Italian Interuniv Consortium Mat Sci & Technol, I-40126 Bologna, Italy
[6] Encapson Co, NL-6503 CB Nijmegen, Netherlands
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 13期
关键词：
atomic force microscopy; molecular recognition; polymers; scanning probe microscopy; single-molecule studies;
D O I：
10.1002/anie.200704526
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) Get a grip! The strategy of single-molecule mechanical unfolding of multimodular proteins is extended to the investigation of any chemical bond by an appropriately tailored, comblike polymer bearing multiple instances of any desired chemical interaction or bond to be studied along its linear chain. This approach is used to study the Ni-(His)n-NTA complex (see picture: red, Ni-NTA; green, His tag; His = histidine; NTA = nitrilotriacetate). © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：2431 / 2434
页数：4
相关论文
共 50 条
  • [21] Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy
    Kolberg, Adrianna
    Wenzel, Christiane
    Hugel, Thorsten
    Gallei, Markus
    Balzer, Bizan N.
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2020, (157):
  • [22] Single-molecule force spectroscopy on poly(acrylic acid) by AFM
    Li, HB
    Liu, BB
    Zhang, X
    Gao, CX
    Shen, JC
    Zou, GT
    LANGMUIR, 1999, 15 (06) : 2120 - 2124
  • [23] Fingerprinting polysaccharides with single-molecule atomic force microscopy (AFM).
    Marszalek, P
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 224 : U398 - U398
  • [24] Polymer functionalized AFM tips for long-term measurements in single-molecule force spectroscopy
    Friedsam, C
    Bécares, AD
    Jonas, U
    Gaub, HF
    Seitz, M
    CHEMPHYSCHEM, 2004, 5 (03) : 388 - 393
  • [25] Blue light-induced low mechanical stability of ruthenium-based coordination bonds: an AFM-based single-molecule force spectroscopy study
    Muddassir, Mohd
    RSC ADVANCES, 2020, 10 (66) : 40543 - 40551
  • [26] AFM-based single molecule force spectroscopy of end-grafted poly(acrylic acid) monolayers
    Sonnenberg, L
    Parvole, J
    Borisov, O
    Billon, L
    Gaub, HE
    Seitz, M
    MACROMOLECULES, 2006, 39 (01) : 281 - 288
  • [27] AFM-based force microsensor for a microrobot
    Fatikow, S
    Fahlbusch, S
    MICROROBOTICS AND MICROASSEMBLY III, 2001, 4568 : 90 - 99
  • [28] Application of Atomic Force Microscopy (AFM)-based Single-molecule Force Spectroscopy (SMFS) in Polymer Characterization
    Zhang, Wei
    Hou, Jue
    Li, Nan
    Zhang, Wen-ke
    ACTA POLYMERICA SINICA, 2021, 52 (11): : 1523 - 1546
  • [29] AFM-Based Single Molecule Techniques: Unraveling the Amyloid Pathogenic Species
    Ruggeri, Francesco Simone
    Habchi, Johnny
    Cerreta, Andrea
    Dietler, Giovanni
    CURRENT PHARMACEUTICAL DESIGN, 2016, 22 (26) : 3950 - 3970
  • [30] AFM-based viscoelasticity measurement for polymeric materials
    Nakajima, Ken
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
12345