Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

被引：2270

作者：

Meanwell, Nicholas A. ^{[1
]}

机构：

[1] Bristol Myers Squibb Pharmaceut Res & Dev, Dept Med Chem, Wallingford, CT 06492 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 2011年 / 54卷 / 08期

关键词：

ADRENOCEPTOR-SELECTIVE ANTAGONISTS; CALCIUM-CHANNEL BLOCKERS; HYDROGEN-BOND BASICITY; CENTER-DOT-O; NONPROSTANOID PROSTACYCLIN MIMETICS; ALPHA-KETOHETEROCYCLIC INHIBITORS; ACTIVE NONPEPTIDIC INHIBITORS; RESPIRATORY SYNCYTIAL VIRUS; ELECTRON-WITHDRAWING POWER; OPIOID AGONIST METABOLITES;

D O I：

10.1021/jm1013693

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：2529 / 2591

页数：63

共 50 条

[1] Some recent tactical application of bioisosteres in drug design
Meanwell, Nicholas A.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
[2] Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
Meanwell, Nicholas A.
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 61 (14) : 5822 - 5880
[3] Applications of bioisosteres in drug design
Meanwell, Nicholas
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
[4] Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design
Subbaiah, Murugaiah A. M.
Meanwell, Nicholas A.
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (19) : 14046 - 14128
[5] The application of bioisosteres in drug design for novel drug discovery: focusing on acid protease inhibitors
Hamada, Yoshio
Kiso, Yoshiaki
EXPERT OPINION ON DRUG DISCOVERY, 2012, 7 (10) : 903 - 922
[6] Squaramides as Bioisosteres in Contemporary Drug Design
Agnew-Francis, Kylie A.
Williams, Craig M.
CHEMICAL REVIEWS, 2020, 120 (20) : 11616 - 11650
[7] Recent Developments in the Practical Application of Novel Carboxylic Acid Bioisosteres
Horgan, Conor
O'Sullivan, Timothy P.
CURRENT MEDICINAL CHEMISTRY, 2022, 29 (13) : 2203 - 2234
[8] APPLICATION OF TACTICAL DESIGN IN CONSTRUCTION OF CODES
RAHMAN, M
IEE PROCEEDINGS-F RADAR AND SIGNAL PROCESSING, 1981, 128 (04) : 222 - 222
[9] Tactical applications of lipophilic efficiency in drug design
Freeman-Cook, Kevin D.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 244
[10] Recent developments concerning the application of the Mannich reaction for drug design
Biersack, Bernhard
Ahmed, Khursheed
Padhye, Subhash
Schobert, Rainer
EXPERT OPINION ON DRUG DISCOVERY, 2018, 13 (01) : 39 - 49

← 1 2 3 4 5 →