Prednisone vs. placebo in withdrawal therapy following medication overuse headache

被引：50
|
作者：
Pageler, L. [1 ,2 ]
Katsarava, Z. [2 ]
Diener, H. C. [2 ]
Limmroth, V. [1 ,2 ]
机构：
[1] Cologne City Hosp, Dept Neurol, Cologne, Germany
[2] Univ Essen Gesamthsch, Dept Neurol, D-4300 Essen, Germany
来源：
CEPHALALGIA | 2008年 / 28卷 / 02期
关键词：
medication overuse headache; medication withdrawal headache; placebo; prednisone;
D O I：
10.1111/j.1468-2982.2007.01488.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
This proof-of-concept study evaluated the efficacy of prednisone for the treatment of withdrawal symptoms in patients with medication overuse headache (MOH) in a randomized, placebo-controlled, double-blind design. Twenty patients were randomized and underwent in-patient withdrawal therapy. The total number of hours with severe or moderate headache within the first 72 and 120 h was significantly lower in the prednisone group. The results show that prednisone might be effective in the treatment of medication withdrawal headache.
引用
收藏
页码：152 / 156
页数：5
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