A new cytotoxic acetogenin from the seeds of Annona squamosa

被引：0
|
作者：
Xie, HH [1 ]
Wei, XY [1 ]
Wang, JD [1 ]
Liu, MF [1 ]
Yang, RZ [1 ]
机构：
[1] Chinese Acad Sci, S China Inst Bot, Guangzhou 510650, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2003年 / 14卷 / 06期
关键词：
Annona squamosa; Annona; acetogenins; squamostolide; cytotoxicity;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new Annonaceous acetogenin, squamostolide (1), was isolated from the seeds of Annona squamosa. Its structure was elucidated based on spectroscopic methods and comparison with known compounds. It is the first example of Annonaceous acetogenin with each of the two ends of the aliphatic chain bearing a gamma-lactone. The new compound exhibited cytotoxic activity in vitro against bel-7402 and CNE2 human tumor cell lines.
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收藏
页码：588 / 590
页数：3
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