Biodegradable hydrogels prepared by gamma-irradiation from microbial poly(amino acid)s are reviewed. pH-sensitive hydrogels were prepared by means of gamma-irradiation of poly(gamma-glutamic acid) (PGA) produced by Bacillus subtilis IF03335 and poly(epsilon-lysine) (PL) produced by Streptomyces albulus in aqueous solutions. The preparation conditions, swelling equilibria, hydrolytic degradation, and enzymatic degradation of these hydrogels were studied. A hydrogel with a wide variety of swelling behaviors has been produced by gamma-irradiation from a mixture solution of PGA and FL.
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MITSUBISHI PAPER MILLS CO LTD,TSUKUBA RES LABS,TSUKUBA,IBARAKI 30042,JAPANMITSUBISHI PAPER MILLS CO LTD,TSUKUBA RES LABS,TSUKUBA,IBARAKI 30042,JAPAN
KUNIOKA, M
GOTO, A
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MITSUBISHI PAPER MILLS CO LTD,TSUKUBA RES LABS,TSUKUBA,IBARAKI 30042,JAPANMITSUBISHI PAPER MILLS CO LTD,TSUKUBA RES LABS,TSUKUBA,IBARAKI 30042,JAPAN