Synthesis, Application, and Properties of Bis(1H-azol-1-yl)methanimines

被引：0
|
作者：
Purygin, P. P. [1 ]
Zarubin, Yu. P. [1 ]
机构：
[1] Samara Natl Res Univ, Samara 443086, Russia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 56卷 / 01期
关键词：
symmetrical and unsymmetrical bis(1H-azol-1-yl)methanimines; hydrolytic stability; biological activity; rat erythrocyte system; 1-CYANOBENZIMIDAZOLE; GUANIDINES;
D O I：
10.1134/S1070428020010170
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The review considers methods of preparation and application of bis(1H-azol-1-yl)methanimines that are imino analogs of 1,1 '-carbonylbisazoles widely used in the synthesis of various organic compounds, including natural ones. Methods of synthesis of a number of new symmetrical and unsymmetrical bisazolylmethanimines derived from imidazole, 2(4)-alkylimidazoles, and 1,2,4-triazole are described, and data on their hydrolytic stability in aqueous-organic medium (aqueous tetrahydrofuran) at 25 degrees C and pH 7 and biological activity with respect to rat erythrocytes are given.
引用
收藏
页码：105 / 112
页数：8
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