Mechanisms of translational regulation in synaptic plasticity

被引：24
|
作者：
Sossin, Wayne S. [1 ]
Lacaille, Jean-Claude [2 ]
机构：
[1] McGill Univ, Dept Neurol & Neurosurg, Montreal, PQ H3A 2B4, Canada
[2] Univ Montreal, GRSNC, Dept Physiol, Montreal, PQ H3C 3J7, Canada
来源：
CURRENT OPINION IN NEUROBIOLOGY | 2010年 / 20卷 / 04期
关键词：
LONG-TERM POTENTIATION; LOCAL PROTEIN-SYNTHESIS; FRAGILE-X-SYNDROME; DENDRITIC SPINE MORPHOGENESIS; HIPPOCAMPAL PYRAMIDAL CELLS; MENTAL-RETARDATION PROTEIN; MESSENGER-RNA LOCALIZATION; DEPENDENT TRANSLATION; MEMORY CONSOLIDATION; SIGNALING PATHWAYS;
D O I：
10.1016/j.conb.2010.03.011
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The plasticity of the nervous system is due to the ability of neurons to change their properties by altering the function of their proteome. A major mechanism for this is through altering the amount of proteins by regulating their translation. In this review, we focus on recent advances in the elucidation of the mechanisms by which neurons regulate translation during synaptic plasticity. Particular focus will be on the different transduction mechanisms that selectively target distinct elements of the mRNA in the regulation of translation during plasticity.
引用
收藏
页码：450 / 456
页数：7
相关论文
共 50 条
  • [21] Recent developments in transcriptional and translational regulation underlying long-term synaptic plasticity and memory
    Hegde, Ashok N.
    Smith, Spencer G.
    LEARNING & MEMORY, 2019, 26 (09) : 307 - 317
  • [22] Degeneracy in the regulation of short-term plasticity and synaptic filtering by presynaptic mechanisms
    Mukunda, Chinmayee L.
    Narayanan, Rishikesh
    JOURNAL OF PHYSIOLOGY-LONDON, 2017, 595 (08): : 2611 - 2637
  • [23] DYNAMIC REGULATION OF MIDBRAIN DOPAMINE NEURON ACTIVITY: INTRINSIC, SYNAPTIC, AND PLASTICITY MECHANISMS
    Morikawa, H.
    Paladini, C. A.
    NEUROSCIENCE, 2011, 198 : 95 - 111
  • [24] Translational control during hippocampal synaptic plasticity and memory
    Klann, Eric
    MOLECULAR PAIN, 2006, 2
  • [25] Translational switch for long term maintenance of synaptic plasticity
    Naveed Aslam
    Yoshi Kubota
    Harel Z Shouval
    BMC Neuroscience, 9 (Suppl 1)
  • [26] MOLECULAR MECHANISMS OF SYNAPTIC PLASTICITY - PREFACE
    RODNIGHT, R
    MOLECULAR NEUROBIOLOGY, 1991, 5 (2-4) : R3 - R4
  • [27] Mechanisms of Homeostatic Synaptic Plasticity in vivo
    Lee, Hey-Kyoung
    Kirkwood, Alfredo
    FRONTIERS IN CELLULAR NEUROSCIENCE, 2019, 13
  • [28] FORMS AND MECHANISMS OF HOMEOSTATIC SYNAPTIC PLASTICITY
    Balashova, A. N.
    Dityatev, A. E.
    Mukhina, I. V.
    SOVREMENNYE TEHNOLOGII V MEDICINE, 2013, 5 (02) : 98 - 105
  • [29] Mechanisms of endocannabinoid control of synaptic plasticity
    Winters, Bryony Laura
    Vaughan, Christopher Walter
    NEUROPHARMACOLOGY, 2021, 197
  • [30] Probing presynaptic mechanisms of synaptic plasticity
    Goda, Y
    GENE TARGETING AND NEW DEVELOPMENTS IN NEUROBIOLOGY, 1996, (19): : 49 - 59
12345