Immunity against cancer: lessons learned from melanoma

被引:157
|
作者
Houghton, AN
Gold, JS
Blachere, NE
机构
[1] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA
[2] Cornell Univ, Weill Med Sch, New York, NY 10021 USA
关键词
D O I
10.1016/S0952-7915(00)00195-3
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Most major advances in human cancer immunology and immunotherapy have come from studies in melanoma. We are beginning to understand the immune repertoire of T cells and antibodies that are active against melanoma, with recent glimpses of the CD4(+) T cell repertoire. The view of what the immune system can see is extending to mutations and parts of the genome that are normally invisible.
引用
收藏
页码:134 / 140
页数:7
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