Functions of long noncoding RNAs in the nucleus

被引：82
|
作者：
Yu, Bin [1 ]
Shan, Ge [1 ]
机构：
[1] Univ Sci & Technol China, Sch Life Sci, CAS Ctr Excellence Mol Cell Sci, CAS Key Lab Innate Immun & Chron Dis, Hefei, Anhui, Peoples R China
来源：
NUCLEUS | 2016年 / 7卷 / 02期
基金：
中国国家自然科学基金;
关键词：
EIciRNA; long noncoding RNA; nuclear; satellite RNA; transcription; DOSAGE COMPENSATION COMPLEX; XIST RNA; CIRCULAR RNAS; HISTONE H3; METHYLTRANSFERASE ACTIVITY; CHROMATIN ACCESSIBILITY; SPLICING REGULATION; GENE-EXPRESSION; X-INACTIVATION; POOR-PROGNOSIS;
D O I：
10.1080/19491034.2016.1179408
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Nucleus is the residence and place of work for a plethora of long noncoding RNAs. Here, we provide a summary of the functions and functional mechanisms of several relatively well studied examples of nuclear long noncoding RNAs (lncRNAs) in the nucleus, such as Xist, NEAT1, MALAT1 and TERRA. The recently identified novel EIciRNA is also highlighted. These nuclear lncRNAs play a variety of roles with diverse molecular mechanisms in animal cells. We also discuss insights and concerns about current and future studies of nuclear lnc RNAs.
引用
收藏
页码：155 / 166
页数：12
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