N-terminal myosin-binding fragment of talin

被引：9

作者：

Lin, Y ^{[1
]}

Kishi, H ^{[1
]}

Nakamura, A ^{[1
]}

Takagi, T ^{[1
]}

Kohama, K ^{[1
]}

机构：

[1] Gunma Univ, Sch Med, Dept Pharmacol, Gunma 3718511, Japan

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1998年 / 249卷 / 03期

基金：

日本学术振兴会;

关键词：

talin; N-terminal 47 KDa fragment; myosin binding; ATPase stimulation;

D O I：

10.1006/bbrc.1998.9000

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Talin, an actin-binding protein from smooth muscle, is shown to bind to myosin in such a way that it stimulates the ATPase activity of myosin irrespective of the phosphorylation state of myosin. The binding site is shown to be localized at the N-terminal, 47 KDa fragment. The position of the actin-binding site at the C terminal suggests that talin may work as a crosslinker between myosin and actin. (C) 1998 Academic Press.

引用

页码：656 / 659

页数：4

共 50 条

[31] Localization of the binding site of the C-terminal domain of cardiac myosin-binding protein-C on the myosin rod
Flashman, Emily
Watkins, Hugh
Redwood, Charles
BIOCHEMICAL JOURNAL, 2007, 401 (01) : 97 - 102
[32] PEPTIDES OF N-TERMINAL FRAGMENT OF PEPSIN MOLECULE
PUGACHEV.IB
STEPANOV, VM
AMIRKHAN.MM
BIOKHIMIYA, 1971, 36 (05): : 993 - &
[33] THE N-TERMINAL DOMAIN OF TALIN - INITIAL STRUCTURAL AND FUNCTIONAL-STUDIES
REES, DJG
GRANT, RP
RAO, ZH
STUART, DI
JOURNAL OF CELLULAR BIOCHEMISTRY, 1994, : 262 - 262
[34] Activation of myocardial contraction by the N-terminal domains of myosin binding protein-C
Herron, Todd J.
Rostkova, Elena
Kunst, Gudrun
Chaturvedi, Rajiv
Gautel, Mathias
Kentish, Jonathan C.
CIRCULATION RESEARCH, 2006, 98 (10) : 1290 - 1298
[35] F-actin binding to the N-terminal region of cardiac myosin binding protein-C
Oakley, Cecily
Hwang, Joo-Mee
Brown, Louise
Kekic, Murat
Fajer, Piotr
Hambly, Brett D.
BIOPHYSICAL JOURNAL, 2007, : 489A - 489A
[36] CHARACTERIZATION OF THE ISOLATED AND RENATURED 23-KDA N-TERMINAL FRAGMENT OF THE MYOSIN HEAVY-CHAIN
MUHLRAD, A
BIOPHYSICAL JOURNAL, 1988, 53 (02) : A238 - A238
[37] Structural prediction and calcium binding analysis of a novel troponin T N-terminal fragment
Root, DD
BIOPHYSICAL JOURNAL, 2004, 86 (01) : 217A - 217A
[38] Heme binding by the N-terminal fragment 1-44 of human growth hormone
Spolaore, B
De Filippis, V
Fontana, A
BIOCHEMISTRY, 2005, 44 (49) : 16079 - 16089
[39] Thioflavin T binding to fibrillar variants of apolipoprotein A-I N-terminal fragment
Girych, M. S.
Gorbenko, G. P.
Trusova, V. M.
Adachi, E.
Mizuguchi, C.
Saito, H.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2013, 42 : S188 - S188
[40] The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate β1 and β3 integrins
Bouaouina, Mohamed
Lad, Yatish
Calderwood, David A.
JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (10) : 6118 - 6125

← 1 2 3 4 5 →