RECURRENT ATRIAL FIBRILLATION IN A PATIENT WITH ULCERATIVE COLITIS TREATED WITH AZATHIOPRINE: CASE REPORT AND REVIEW OF THE LITERATURE

被引：14

作者：

Riccioni, G. ^{[1
]}

Bucciarelli, V. ^{[2
]}

Di Ilio, E. ^{[2
]}

Scotti, L. ^{[2
]}

Aceto, A. ^{[2
]}

D'Orazio, N. ^{[2
]}

Martini, F. ^{[2
]}

Bucciarelli, T. ^{[2
]}

机构：

[1] San Camillo De Lellis Hosp, Cardiol Unit, Foggia, Italy

[2] Univ G DAnnunzio, Dept Biomed Sci, Chieti, Italy

来源：

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2011年 / 24卷 / 01期

关键词：

azathioprine; ulcerative colitis; atrial fibrillation;

D O I：

10.1177/039463201102400131

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We present a clinical case report regarding recurrent atrial fibrillation in a patient with ulcerative colitis treated with azathioprine. Atrial fibrillation represents the most common sustained cardiac arrhythmia, occurring in 1-2% of the general population and characterized by seemingly disorganized atrial depolarizations without effective atrial contraction. Several mechanisms determine this arrhythmia; in particular remodelling (structural, mechanical and electrical alteration related to atrial fibrillation). The pro-arrhythmic effect of azathioprine may be evaluated during immunosuppressive therapy to be aware of this serious but reversible adverse effect.

引用

页码：247 / 249

页数：3

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