RECURRENT ATRIAL FIBRILLATION IN A PATIENT WITH ULCERATIVE COLITIS TREATED WITH AZATHIOPRINE: CASE REPORT AND REVIEW OF THE LITERATURE

被引：14
|
作者：
Riccioni, G. [1 ]
Bucciarelli, V. [2 ]
Di Ilio, E. [2 ]
Scotti, L. [2 ]
Aceto, A. [2 ]
D'Orazio, N. [2 ]
Martini, F. [2 ]
Bucciarelli, T. [2 ]
机构：
[1] San Camillo De Lellis Hosp, Cardiol Unit, Foggia, Italy
[2] Univ G DAnnunzio, Dept Biomed Sci, Chieti, Italy
来源：
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY | 2011年 / 24卷 / 01期
关键词：
azathioprine; ulcerative colitis; atrial fibrillation;
D O I：
10.1177/039463201102400131
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We present a clinical case report regarding recurrent atrial fibrillation in a patient with ulcerative colitis treated with azathioprine. Atrial fibrillation represents the most common sustained cardiac arrhythmia, occurring in 1-2% of the general population and characterized by seemingly disorganized atrial depolarizations without effective atrial contraction. Several mechanisms determine this arrhythmia; in particular remodelling (structural, mechanical and electrical alteration related to atrial fibrillation). The pro-arrhythmic effect of azathioprine may be evaluated during immunosuppressive therapy to be aware of this serious but reversible adverse effect.
引用
收藏
页码：247 / 249
页数：3
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