Epilepsy is commonly encountered in neurology practice, affecting more than 50 million people worldwide, according to the World Health Organization reports. Management of women with epilepsy requires attention to some considerations including the hormonal changes and its impact on epilepsy, the interaction between oral contraceptives and antiepileptic drugs (AEDs), pregnancy, and the potential teratogenic risk associated with AEDs use during that period. Similarly, the effect of AEDs on bone health should always be considered, and measures should be taken to reduce the risk of osteoporosis given the fact that women in their menopause are at increased risk. Despite the considerable risk of teratogenicity with AEDs use in pregnancy, more than 90% of pregnancies will be uneventful.
机构:
Hop La Pitie Salpetriere, AP HP, Epilepsy Unit, 47 Blvd Hop, F-75013 Paris, France
Hop La Pitie Salpetriere, AP HP, Rehabil Unit, 47 Blvd Hop, F-75013 Paris, France
INSERM, Inst Cerveau & Moelle Epiniere ICM, Ctr Rech, CNRS,UMRS 975,UMPC,UMR 7225, 47 Blvd Hop, F-75013 Paris, France
Sorbonne Univ, Paris 6, FranceHop La Pitie Salpetriere, AP HP, Epilepsy Unit, 47 Blvd Hop, F-75013 Paris, France
机构:
Rush Univ, Rush Presbyterian St Lukes Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USARush Univ, Rush Presbyterian St Lukes Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA
LaVaccare, JA
Bergen, D
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机构:
Rush Univ, Rush Presbyterian St Lukes Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USARush Univ, Rush Presbyterian St Lukes Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA