Cell cycle length and long-time behavior of an age-size model

被引:4
|
作者
Pichor, Katarzyna [1 ]
Rudnicki, Ryszard [2 ]
机构
[1] Univ Silesia, Inst Math, Katowice, Poland
[2] Polish Acad Sci, Inst Math, Bankowa 14, PL-40007 Katowice, Poland
关键词
asynchronous exponential growth; cell cycle; semigroup of operators; size-age structured model; ASYMPTOTIC-BEHAVIOR; MARKOV SEMIGROUPS; DIVISION; GROWTH; POPULATIONS; STABILITY; EQUATION; BACTERIA;
D O I
10.1002/mma.8139
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
We consider an age-size structured cell population model based on the cell cycle length. The model is described by a first order partial differential equation with initial-boundary conditions. Using the theory of semigroups of positive operators, we establish new criteria for an asynchronous exponential growth of solutions to such equations. We discuss the question of exponential size growth of cells. We study in detail a constant size growth model and a model with target size division. We also present versions of the model when the population is heterogeneous.
引用
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页码:5797 / 5820
页数:24
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