The authors report a patient with chorea and multifocal neurologic abnormalities associated with a small-cell lung carcinoma. A previously unreported antibody directed at a 76-kD neuronal protein antigen was identified in both serum and CSF. Antitumor treatment resulted in dramatic and sustained clinical neurologic and serologic responses.
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Capital Med Univ, Beijing Chaoyang Hosp, Dept Neurol, Gongti South 8th, Beijing 100020, Peoples R ChinaCapital Med Univ, Beijing Chaoyang Hosp, Dept Neurol, Gongti South 8th, Beijing 100020, Peoples R China
Yuan, Junliang
Jia, Zejin
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Capital Med Univ, Beijing Chaoyang Hosp, Dept Neurol, Gongti South 8th, Beijing 100020, Peoples R ChinaCapital Med Univ, Beijing Chaoyang Hosp, Dept Neurol, Gongti South 8th, Beijing 100020, Peoples R China
Jia, Zejin
Qin, Wei
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Capital Med Univ, Beijing Chaoyang Hosp, Dept Neurol, Gongti South 8th, Beijing 100020, Peoples R ChinaCapital Med Univ, Beijing Chaoyang Hosp, Dept Neurol, Gongti South 8th, Beijing 100020, Peoples R China
Qin, Wei
Hu, Wenli
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Capital Med Univ, Beijing Chaoyang Hosp, Dept Neurol, Gongti South 8th, Beijing 100020, Peoples R ChinaCapital Med Univ, Beijing Chaoyang Hosp, Dept Neurol, Gongti South 8th, Beijing 100020, Peoples R China