Ocular Juvenile Xanthogranuloma With BRAF V600E Mutation in a Child

被引：3
|
作者：
Zhang, Chengyue [1 ]
Feng, Zhao Xun [2 ]
Solarte, Carlos E. [1 ]
Li, Li [1 ]
机构：
[1] Capital Med Univ, Natl Ctr Childrens Hlth, Beijing Childrens Hosp, Dept Ophthalmol, Beijing, Peoples R China
[2] Univ Ottawa, Ottawa, ON, Canada
来源：
JOURNAL OF PEDIATRIC OPHTHALMOLOGY & STRABISMUS | 2021年 / 58卷 / 04期
关键词：
D O I：
10.3928/01913913-20210416-01
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
The authors present a case of bilateral painless progressive proptosis. A diagnosis of ocular juvenile xanthogranuloma was made based on clinical manifestations, histopathology, and immunohistochemistrical staining. Genetic testing discovered the BRAF V600E mutation. This patient did not respond to standard chemotherapy; however, he demonstrated regression after anti-BRAF targeted therapy.
引用
收藏
页码：E19 / E21
页数：3
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